Equity-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2019

Share-based Payment Arrangement [Abstract]

Summary of details regarding stock option activity

The following table summarizes stock option activity for the six months ended June 30, 2019:

	2019 Equity	2007 Equity		2013 Lumara		Inducement
	Plan	Plan		Equity Plan		Grants		Total
Outstanding at December 31, 2018	—	2,781,786		124,450		810,343		3,716,579
Granted	145,408	465,009		34,700		49,166		694,283
Exercised	—	(2,025	)	—		—		(2,025	)
Expired or terminated	—	(482,768	)	(26,275	)	(68,250	)	(577,293	)
Outstanding at June 30, 2019	145,408	2,762,002		132,875		791,259		3,831,544

Summary of details regarding restricted stock activity

The following table summarizes RSU activity for the six months ended June 30, 2019:

	2019 Equity	2007 Equity		2013 Lumara		Inducement
	Plan	Plan		Equity Plan		Grants		Total
Outstanding at December 31, 2018	—	1,041,141		2,101		85,293		1,128,535
Granted	64,928	1,023,847		1,100		13,385		1,103,260
Vested	—	(348,845	)	(533	)	(29,076	)	(378,454	)
Expired or terminated	—	(231,855	)	—		—		(231,855	)
Outstanding at June 30, 2019	64,928	1,484,288		2,668		69,602		1,621,486

Schedule of equity-based compensation expense

Equity-based compensation expense for the three and six months ended June 30, 2019 and 2018 consisted of the following (in thousands):

	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Cost of product sales	$	198	$	107	$	401	$	307
Research and development	680		608		1,360		1,328
Selling, general and administrative	3,656		4,077		6,981		7,948
Total equity-based compensation expense	4,534		4,792		8,742		9,583
Income tax effect	—		835		—		—
After-tax effect of equity-based compensation expense	$	4,534	$	5,627	$	8,742	$	9,583