CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Revenues:
Revenues	$ 78,109	$ 146,254	$ 153,913	$ 263,642
Costs and expenses:
Cost of product sales	24,290	76,776	42,767	140,688
Research and development expenses	14,980	11,693	33,046	22,502
Acquired in-process research and development	0	0	74,856	20,000
Selling, general and administrative expenses	77,324	15,898	152,006	89,329
Impairment of intangible assets	77,358	0	77,358	0
Restructuring expenses	0	0	7,420	0
Total costs and expenses	193,952	104,367	387,453	272,519
Operating (loss) income	(115,843)	41,887	(233,540)	(8,877)
Other income (expense):
Interest expense	(6,330)	(16,056)	(12,780)	(32,034)
Interest and dividend income	1,224	952	2,810	1,595
Other income (expense)	2	(44)	342	(44)
Total other expense, net	(5,104)	(15,148)	(9,628)	(30,483)
(Loss) income from continuing operations before income taxes	(120,947)	26,739	(243,168)	(39,360)
Income tax (benefit) expense	(120)	52,556	(257)	44,556
Net loss from continuing operations	(120,827)	(25,817)	(242,911)	(83,916)
Discontinued operations:
Income from discontinued operations	0	7,158	0	13,036
Income tax expense	0	1,422	0	3,444
Net income from discontinued operations	0	5,736	0	9,592
Net loss	$ (120,827)	$ (20,081)	$ (242,911)	$ (74,324)
Basic and diluted net (loss) income per share:
Loss from continuing operations (in dollars per share)	$ (3.57)	$ (0.75)	$ (7.12)	$ (2.45)
Income from discontinued operations (in dollars per share)	0	0.17	0	0.28
Basic and diluted net loss per share (in dollars per share)	$ (3.57)	$ (0.58)	$ (7.12)	$ (2.17)
Weighted average shares outstanding used to compute net (loss) per share (basic and diluted) (in shares)	33,807	34,358	34,136	34,261
Product Sales
Revenues:
Revenues	$ 77,976	$ 146,219	$ 153,705	$ 263,567
Other revenues
Revenues:
Revenues	$ 133	$ 35	$ 208	$ 75