Equity-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2019

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Summary of details regarding stock option activity

The following table summarizes stock option activity for the three months ended March 31, 2019:

	2007 Equity		2013 Lumara		Inducement
	Plan		Equity Plan		Grants		Total
Outstanding at December 31, 2018	2,781,786		124,450		810,343		3,716,579
Granted	358,683		26,400		16,500		401,583
Exercised	(2,025	)	—		—		(2,025	)
Expired or terminated	(214,881	)	(10,613	)	(2,250	)	(227,744	)
Outstanding at March 31, 2019	2,923,563		140,237		824,593		3,888,393

Summary of details regarding restricted stock activity

The following table summarizes RSU activity for the three months ended March 31, 2019:

	2007 Equity		2013 Lumara	Inducement
	Plan		Equity Plan	Grants		Total
Outstanding at December 31, 2018	1,041,141		2,101	85,293		1,128,535
Granted	1,007,719		1,100	2,100		1,010,919
Vested	(309,877	)	—	(10,669	)	(320,546	)
Expired or terminated	(99,163	)	—	—		(99,163	)
Outstanding at March 31, 2019	1,639,820		3,201	76,724		1,719,745

Schedule of equity-based compensation expense

Equity-based compensation expense for the three months ended March 31, 2019 and 2018 consisted of the following (in thousands):

	Three Months Ended March 31,
	2019		2018
Cost of product sales	$	202	$	200
Research and development	680		720
Selling, general and administrative	3,325		3,870
Total equity-based compensation expense	4,207		4,790
Income tax effect	—		(835		)
After-tax effect of equity-based compensation expense	$	4,207	$	3,955