CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Revenues:
Revenues	$ 75,804	$ 117,387
Costs and expenses:
Cost of product sales	18,477	63,912
Research and development expenses	18,066	10,809
Acquired in-process research and development	74,856	20,000
Selling, general and administrative expenses	74,682	73,431
Restructuring expenses	7,420	0
Total costs and expenses	193,501	168,152
Operating loss	(117,697)	(50,765)
Other income (expense):
Interest expense	(6,450)	(15,977)
Interest and dividend income	1,586	643
Other income	340	0
Total other expense, net	(4,524)	(15,334)
Loss from continuing operations before income taxes	(122,221)	(66,099)
Income tax benefit	(137)	(8,000)
Net loss from continuing operations	(122,084)	(58,099)
Discontinued operations:
Income from discontinued operations	0	5,878
Income tax expense	0	2,021
Net income from discontinued operations	0	3,857
Net loss	$ (122,084)	$ (54,242)
Basic and diluted net income (loss) per share:
Loss from continuing operations (in dollars per share)	$ (3.54)	$ (1.70)
Income (loss) from discontinued operations (in dollars per share)	0.00	0.11
Basic and diluted net loss per share (in dollars per share)	$ (3.54)	$ (1.59)
Weighted average shares outstanding used to compute net loss per share:
Weighted average shares outstanding used to compute net loss per share (basic and diluted) (in shares)	34,469	34,162
Product Sales
Revenues:
Revenues	$ 75,729	$ 117,348
Other revenues
Revenues:
Revenues	$ 75	$ 39