Income Taxes - Deferred Tax Components (Details) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Assets
Net operating loss carryforwards	$ 46,888	$ 60,308
Tax credit carryforwards	24,290	15,577
Capital loss carryforwards	20,896	0
Interest expense carryforwards	4,318	0
Equity-based compensation expense	5,931	5,873
Capitalized research & development	4,635	7,872
Intangible assets	12,565	0
Reserves	2,683	3,342
Contingent consideration	87	1,406
Other	5,389	5,971
Valuation allowance	(113,278)	(4,740)
Liabilities
Property, plant and equipment depreciation	(614)	(198)
Intangible assets and inventory	0	(32,406)
Debt instruments	(12,489)	(15,744)
Other	(41)	(141)
Net deferred tax assets	$ 1,260	$ 47,120