Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 4
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=109196051&loc=SL49130543-203045

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=109196051&loc=SL49130539-203045

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 5
-URI http://asc.fasb.org/extlink&oid=109196051&loc=SL49130545-203045

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Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

Revenue Recognition - Total Gross Product (Details) - USD ($) $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2017	Sep. 30, 2017	Jun. 30, 2017	Mar. 31, 2017	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Provision for product sales allowances and accruals:
Product sales, net	$ 88,122	$ 122,238	$ 146,254	$ 117,387	$ 128,525	$ 124,331	$ 130,371	$ 112,541	$ 474,002	$ 495,769	$ 432,487
Product
Disaggregation of Revenue [Line Items]
Gross product sales									974,330	920,061	748,839
Provision for product sales allowances and accruals:
Contractual adjustments									387,540	310,588	229,686
Governmental rebates									112,938	113,828	86,983
Total									500,478	424,416	316,669
Product sales, net									$ 473,852	$ 495,645	$ 432,170