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Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2018
Accounting Policies [Abstract]  
Schedule of customers representing greater than 10% of revenues/accounts receivable balances
The following table sets forth customers who represented 10% or more of our total revenues for 2018, 2017 and 2016:
 
Years Ended December 31,
 
2018

2017

2016
AmerisourceBergen Drug Corporation
27%
 
26%
 
27%
McKesson Corporation
26%
 
24%
 
14%
Caremark, LLC
< 10%

< 10%

10%
Schedule of property and equipment estimated useful lives
Property and equipment are recorded at cost and depreciated when placed into service using the straight-line method based on their estimated useful lives as follows:
 
Useful Life
Computer equipment and software
5 Years
Furniture and fixtures
5 Years
Leasehold improvements
Lesser of Lease or Asset Life
Laboratory and production equipment
5 Years / 8 Years
Property and equipment, net consisted of the following as of December 31, 2018 and 2017 (in thousands):
 
December 31,
 
2018
 
2017
Computer equipment and software
$
1,637

 
$
1,401

Furniture and fixtures
1,737

 
1,442

Leasehold improvements
2,938

 
2,938

Laboratory and production equipment
6,000

 
654

Construction in progress
420

 
5,068

 
12,732

 
11,503

Less: accumulated depreciation
(5,211
)
 
(3,599
)
Property and equipment, net
$
7,521

 
$
7,904

Schedule of components of basic and diluted net income (loss) per share
The components of basic and diluted net (loss) income per share for 2018, 2017 and 2016 were as follows (in thousands, except per share data):
 
Years Ended December 31,
 
2018
 
2017
 
2016
Net (loss) income from continuing operations
$
(169,339
)
 
$
(205,153
)
 
$
2,093

Net income (loss) from discontinued operations
103,578

 
5,925

 
(4,576
)
 
 

 
 

 
 

Weighted average common shares outstanding
34,394

 
34,907

 
34,346

Effect of dilutive securities:
 

 
 

 
 

Stock options and RSUs

 

 
487

Shares used in calculating dilutive net loss per share
34,394

 
34,907

 
34,833

 
 

 
 

 
 

Basic net (loss) income per share:
 

 
 

 
 

(Loss) income from continuing operations
$
(4.92
)
 
$
(5.88
)
 
$
0.06

Income (loss) from discontinued operations
3.01

 
0.17

 
(0.13
)
Total
$
(1.91
)
 
$
(5.71
)
 
$
(0.07
)
 
 
 
 
 
 
Diluted net (loss) income per share:
 
 
 
 
 
(Loss) income from continuing operations
$
(4.92
)
 
$
(5.88
)
 
$
0.06

Income (loss) from discontinued operations
3.01

 
0.17

 
(0.13
)
Total
$
(1.91
)
 
$
(5.71
)
 
$
(0.07
)
Schedule of anti-dilutive securities from computation of diluted net (loss) income per share
The following table sets forth the potential common shares issuable upon the exercise of outstanding options, the purchase of shares under our employee stock purchase plan, the vesting of RSUs, the exercise of warrants (prior to consideration of the treasury stock method), and the conversion of the Convertible Notes, which were excluded from our computation of diluted net (loss) income per share because their inclusion would have been anti-dilutive (in thousands):
 
Years Ended December 31,
 
2018
 
2017
 
2016
Options to purchase shares of common stock
3,797

 
3,531

 
2,590

Shares of common stock issuable upon the vesting of RSUs
1,129

 
1,070

 
613

Warrants
1,008

 
1,008

 
7,382

2022 Convertible Notes
11,695

 
11,695

 

2019 Convertible Notes
790

 
790

 
7,382

Shares of common stock under employee stock purchase plan
81

 

36

Total
18,500

 
18,094

 
18,003