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Consolidated Quarterly Financial Data - Unaudited (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Feb. 28, 2017
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Condensed Financial Information Disclosure [Abstract]                        
Total revenues   $ 88,122 $ 122,238 $ 146,254 $ 117,387 $ 128,525 $ 124,331 $ 130,371 $ 112,541 $ 474,002 $ 495,769 $ 432,487
Gross profit   59,406 75,749 69,478 53,475 57,938 (226,000) 98,270 84,968      
Operating expenses   78,241 95,084 27,591 104,239 70,663 28,236 95,003 125,112      
Net (loss) income from continuing operations   (20,746) (64,678) (25,817) (58,098) 738 (155,713) (14,252) (35,925) (169,339) (205,153) 2,093
Net (loss) income from discontinued operations   (1,531) 95,517 5,736 3,856 2,722 3,652 186 (635) 103,578 5,925 (4,576)
Net loss   $ (22,277) $ 30,839 $ (20,081) $ (54,242) $ 3,460 $ (152,061) $ (14,066) $ (36,560) $ (65,761) $ (199,228) $ (2,483)
Basic net (loss) income per share:                        
(Loss) income from continuing operations (in dollars per share)   $ (0.60) $ (1.88) $ (0.75) $ (1.70) $ 0.02 $ (4.41) $ (0.41) $ (1.04) $ (4.92) $ (5.88) $ 0.06
(Loss) income from discontinued operations (in dollars per share)   (0.04) 2.77 0.17 0.11 0.08 0.10 0.01 (0.02) 3.01 0.17 (0.13)
Total (in dollars per share)   (0.64) 0.89 (0.58) (1.59) 0.10 (4.31) (0.40) (1.06) (1.91) (5.71) (0.07)
Diluted net (loss) income per share:                        
(Loss) income from continuing operations (in dollars per share)   (0.60) (1.88) (0.75) (1.70) 0.02 (4.41) (0.41) (1.04) (4.92) (5.88) 0.06
Income (loss) from discontinued operations (in dollars per share)   (0.04) 2.77 0.17 0.11 0.08 0.10 0.01 (0.02) 3.01 0.17 (0.13)
Total (in dollars per share)   $ (0.64) $ 0.89 $ (0.58) $ (1.59) $ 0.10 $ (4.31) $ (0.40) $ (1.06) $ (1.91) $ (5.71) $ (0.07)
Condensed Financial Statements, Captions [Line Items]                        
Impairment of intangible assets                   $ 0 $ 319,246 $ 15,724
Makena                        
Condensed Financial Information Disclosure [Abstract]                        
Total revenues                   322,265 387,158 $ 334,050
Makena | Developed technology rights                        
Condensed Financial Statements, Captions [Line Items]                        
Impairment of intangible assets             $ 319,200          
Contingent Consideration                        
Condensed Financial Statements, Captions [Line Items]                        
Adjustments to fair value of contingent consideration       $ 49,800     $ 49,900     $ (49,607) $ (47,686)  
Palatin Technologies, Inc.                        
Condensed Financial Statements, Captions [Line Items]                        
Upfront payment $ 60,000               $ 60,000