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Fair Value Measurements - Contingent Consideration (Details)
$ in Thousands
9 Months Ended
Sep. 30, 2018
USD ($)
Nov. 30, 2014
USD ($)
MuGard    
Reconciliation of contingent consideration obligations related to acquisitions    
Estimated undiscounted royalty amounts payable, minimum $ 2,000  
Estimated undiscounted royalty amounts payable, maximum $ 6,000  
Period over which estimated undiscounted royalty amounts could be paid 10 years  
Contingent Consideration    
Reconciliation of contingent consideration obligations related to acquisitions    
Balance at beginning of period $ 50,085  
Payments made (87)  
Adjustments to fair value of contingent consideration (49,175)  
Balance at end of period $ 823  
Lumara Health Inc.    
Reconciliation of contingent consideration obligations related to acquisitions    
Estimated undiscounted royalty amounts payable, maximum   $ 350,000
Measurement Input, Discount Rate | MuGard    
Reconciliation of contingent consideration obligations related to acquisitions    
Discount rate 0.13