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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Statement of Cash Flows [Abstract]    
Net loss $ (74,324) $ (50,626)
Adjustments to reconcile net loss to net cash provided by operating activities:    
Depreciation and amortization 126,183 59,563
Provision for bad debt expense 856 2,681
Amortization of premium/discount on purchased securities 93 168
Gain on disposal of fixed assets (99) 0
Non-cash equity-based compensation expense 11,122 11,669
Non-cash IPR&D expense 0 945
Loss on debt extinguishment 0 9,516
Amortization of debt discount and debt issuance costs 7,851 6,679
Gains on marketable securities, net 0 (249)
Change in fair value of contingent consideration (49,184) 2,786
Deferred income taxes 42,372 (29,677)
Prepaid transaction costs (3,865) 0
Changes in operating assets and liabilities:    
Accounts receivable, net (11,265) 233
Inventories 1,223 (1,145)
Prepaid and other current assets (756) (1,178)
Accounts payable and accrued expenses 27,475 40,716
Deferred revenues 7,329 7,380
Other assets and liabilities 117 (1,029)
Net cash provided by operating activities 85,128 58,432
Cash flows from investing activities:    
Proceeds from sales or maturities of marketable securities 44,038 251,017
Purchase of marketable securities (46,726) (85,249)
Acquisition of Intrarosa intangible asset 0 (46,500)
Capital expenditures (1,553) (2,672)
Net cash (used in) provided by investing activities (4,241) 116,596
Cash flows from financing activities:    
Long-term debt principal payments 0 (328,125)
Proceeds from 2022 Convertible Notes 0 320,000
Payment to repurchase 2019 Convertible Notes 0 (170,371)
Proceeds to settle warrants 0 323
Payment of convertible debt issuance costs 0 (9,553)
Payments of contingent consideration (60) (119)
Proceeds from the exercise of common stock options 1,473 1,130
Payments of employee tax withholding related to equity-based compensation (2,362) (2,439)
Net cash used in financing activities (949) (189,154)
Net increase (decrease) in cash, cash equivalents, and restricted cash 79,938 (14,126)
Cash, cash equivalents, and restricted cash related to discontinued operations (59,714) (62,622)
Cash, cash equivalents, and restricted cash at beginning of the period 192,770 276,898
Cash, cash equivalents, and restricted cash at end of the period 212,994 200,150
Supplemental data for cash flow information:    
Cash paid for taxes 4,181 3,191
Cash paid for interest 24,171 29,173
Non-cash investing and financing activities:    
Fair value of common stock issued in connection with the acquisition of the Intrarosa intangible asset 0 12,555
Contingent consideration accrued for the acquisition of the Intrarosa intangible asset $ 0 $ 18,600