CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Revenues:
Product sales, net	$ 117,348	$ 112,517
Service revenues, net	28,969	26,931
Other revenues	39	24
Total revenues	146,356	139,472
Costs and expenses:
Cost of product sales	63,912	27,573
Cost of services	5,473	5,010
Research and development expenses	10,809	16,489
Acquired in-process research and development	20,000	60,000
Selling, general and administrative expenses	91,050	70,424
Total costs and expenses	191,244	179,496
Operating loss	(44,888)	(40,024)
Other (expense) income:
Interest expense	(15,977)	(18,300)
Interest and dividend income	644	1,031
Gains on investments, net	0	27
Total other expense, net	(15,333)	(17,242)
Loss before income taxes	(60,221)	(57,266)
Income tax benefit	(5,979)	(20,706)
Net loss	$ (54,242)	$ (36,560)
Net loss per share:
Basic and diluted (in usd per share)	$ (1.59)	$ (1.06)
Weighted average shares outstanding used to compute net loss per share:
Basic and diluted (in shares)	34,162	34,378