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Income Taxes - Narrative (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2017
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Tax Credit Carryforward [Line Items]          
Income tax (benefit) expense   $ (170,866) $ 11,538 $ 7,065  
Effective tax rate 46.20% 46.20% 127.40% 17.70%  
Provisional tax benefit   $ 17,600      
Increase in valuation allowance   4,200      
Unrecognized tax benefits $ 10,870 10,870 $ 13,330 $ 12,695 $ 0
Unrecognized tax benefits that would impact effective tax rate 10,700 10,700 13,000 $ 12,400  
Increase (decrease) in unrecognized tax benefits   (2,500) $ 600    
CBR          
Tax Credit Carryforward [Line Items]          
Operating loss carryforwards 10,900 10,900      
Internal Revenue Service (IRS)          
Tax Credit Carryforward [Line Items]          
Operating loss carryforwards 265,800 265,800      
Tax credit carryforward, amount 14,800 14,800      
Internal Revenue Service (IRS) | Lumara Health          
Tax Credit Carryforward [Line Items]          
Operating loss carryforwards 165,500 165,500      
Tax credit carryforward, amount 1,500 1,500      
State and Local Jurisdiction          
Tax Credit Carryforward [Line Items]          
Operating loss carryforwards 90,900 90,900      
Tax credit carryforward, amount 1,400 1,400      
State and Local Jurisdiction | Lumara Health          
Tax Credit Carryforward [Line Items]          
Operating loss carryforwards $ 16,600 $ 16,600