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Goodwill and Intangible Assets, Net - Goodwill - Narrative (Details) - USD ($)
3 Months Ended 12 Months Ended
Oct. 31, 2017
Sep. 30, 2017
Sep. 30, 2017
Jun. 30, 2016
Dec. 31, 2015
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Aug. 17, 2015
Nov. 12, 2014
Feb. 11, 2014
Goodwill [Line Items]                      
Goodwill         $ 639,188,000 $ 639,484,000 $ 639,484,000 $ 639,188,000      
Increase in goodwill             296,000        
Accumulated impairment losses           0          
Impairment of intangible assets           $ 319,246,000 19,663,000 0      
Share price (USD per share)   $ 18.45 $ 18.45               $ 20.07
Market capitalization   $ 653,000,000 $ 653,000,000                
Fair value percentage below carrying amount, reporting unit   18.00%                  
Fair value percentage above carrying amount, net assets   6.00%                  
Goodwill, impairment $ 0 $ 0         $ 0 $ 0      
Fair value inputs, discount rate, sensitivity analysis of one percent 1.00%                    
Fair value percentage above carrying amount, reporting unit 18.00%                    
Lumara Health Inc.                      
Goodwill [Line Items]                      
Goodwill                   $ 198,100,000  
CBR                      
Goodwill [Line Items]                      
Goodwill                 $ 441,371,000    
Increase in goodwill       $ 300,000 $ 1,800,000            
Makena | Makena base technology                      
Goodwill [Line Items]                      
Impairment of intangible assets     $ 319,200,000                
Minimum                      
Goodwill [Line Items]                      
Fair value inputs, control premium     30.00%                
Discount rate 10.00%                    
Maximum                      
Goodwill [Line Items]                      
Fair value inputs, control premium     83.00%                
Discount rate 19.50%                    
Weighted Average                      
Goodwill [Line Items]                      
Fair value inputs, control premium     64.00%                
Discount rate 13.60%