Property, Plant and Equipment, Net (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 45,486	$ 38,553
Less: accumulated depreciation	(19,490)	(14,093)
Property, plant and equipment, net	25,996	24,460
Depreciation expense	7,200	9,200	$ 3,900
Land
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	700	700
Land improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	300	300
Building and improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	9,552	9,500
Computer equipment and software
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	14,073	13,866
Furniture and fixtures
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	2,512	2,401
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	4,959	3,718
Laboratory and production equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	8,030	6,449
Construction in progress
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 5,360	$ 1,619