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Summary of Significant Accounting Policies - Property, Plant and Equipment, Net (Details)
12 Months Ended
Dec. 31, 2017
Buildings and improvements | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 15 years
Buildings and improvements | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 40 years
Computer equipment and software  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 5 years
Furniture and fixtures  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 5 years
Laboratory and production equipment  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 5 years
Land improvements  
Property, Plant and Equipment [Line Items]  
Estimated useful lives 10 years