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Collaboration, License and Other Strategic Agreements (Details) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Apr. 03, 2017
Feb. 28, 2017
Jul. 31, 2015
Jun. 30, 2017
Sep. 30, 2015
Sep. 30, 2017
Sep. 30, 2016
Dec. 31, 2016
Collaborative Agreements                
Net shares issued in connection with license agreement, value           $ 12,555,000 $ 0  
Finite-lived intangible assets           1,171,755,000   $ 1,094,100,000
Velo Bio option agreement                
Collaborative Agreements                
Upfront payment, option agreement         $ 10,000,000      
Payments due     $ 65,000,000          
Sales milestone payments based on annual sales milestones     $ 250,000,000          
Covenant, royalty rate     0.00%          
Increase of milestone payment when royalty rate is zero     50.00%          
Minimum | Velo Bio option agreement                
Collaborative Agreements                
Sales milestone targets     $ 100,000,000          
Maximum | Velo Bio option agreement                
Collaborative Agreements                
Sales milestone targets     $ 900,000,000          
Endoceutics License Agreement                
Collaborative Agreements                
Upfront payment $ 50,000,000              
Number of shares issued under arrangement 600,000              
Net shares issued in connection with license agreement, value $ 13,500,000         $ 13,500,000    
Consideration recorded       $ 83,500,000        
IPR&D expense       5,800,000        
Period after first commercial sale 10 years         10 years    
Transfer of intellectual property to second source supplier, term (within) 2 years              
Endoceutics License Agreement | Research and Development Arrangement                
Collaborative Agreements                
Out-of-pocket expenses (up to) $ 20,000,000.0              
Endoceutics License Agreement | Intrarosa developed technology                
Collaborative Agreements                
Finite-lived intangible assets       $ 77,700,000        
Endoceutics License Agreement | Anniversary of Closing                
Collaborative Agreements                
Maximum future contingent payments           $ 10,000,000    
Endoceutics License Agreement | Delivery of Launch Quantities                
Collaborative Agreements                
Maximum future contingent payments           10,000,000    
Endoceutics License Agreement | Tiered Royalties                
Collaborative Agreements                
Maximum future contingent payments $ 150,000,000.0         $ 150,000,000.0    
Royalty percentage, maximum 20.00%         20.00%    
Net sales threshold, future contingent payments $ 1,000,000,000.0         $ 1,000,000,000.0    
Endoceutics License Agreement | First Sales Milestone | Endoceutics, Inc.                
Collaborative Agreements                
Sales milestone 15,000,000.0         15,000,000.0    
Sales milestone, triggering amount 150,000,000.0         150,000,000.0    
Endoceutics License Agreement | Second Sales Milestone | Endoceutics, Inc.                
Collaborative Agreements                
Sales milestone 30,000,000.0         30,000,000.0    
Sales milestone, triggering amount 300,000,000.0         300,000,000.0    
Endoceutics License Agreement | Third Sales Milestone | Endoceutics, Inc.                
Collaborative Agreements                
Sales milestone 850,000,000.0         850,000,000.0    
Sales milestone, triggering amount $ 500,000,000.0         500,000,000.0    
Endoceutics License Agreement | 180 Day Lock-Up Provision                
Collaborative Agreements                
Number of shares issued under arrangement 300,000              
Stock issued, lock-up period 180 days              
Endoceutics License Agreement | One Year Lock-Up Provision                
Collaborative Agreements                
Number of shares issued under arrangement 300,000              
Stock issued, lock-up period 1 year              
Palatin License Agreement | License Agreement Terms                
Collaborative Agreements                
Maximum future contingent payments           380,000,000.0    
Upfront payment   $ 60,000,000            
Maximum reimbursement   $ 25,000,000.0            
Expiration period, following first commercial sale   10 years            
Palatin License Agreement | First Sales Milestone | License Agreement Terms                
Collaborative Agreements                
Maximum future contingent payments   $ 300,000,000.0            
Sales milestone   25,000,000.0            
Sales milestone, triggering amount   250,000,000.0            
Palatin License Agreement | Regulatory milestone | License Agreement Terms                
Collaborative Agreements                
Maximum future contingent payments   $ 80,000,000.0            
Palatin License Agreement | Regulatory milestone, acceptance by U.S. Food and Drug Administration for new drug application | License Agreement Terms                
Collaborative Agreements                
Maximum future contingent payments           20,000,000    
Palatin License Agreement | Regulatory milestone, U.S. Food and Drug Administration approval | License Agreement Terms                
Collaborative Agreements                
Maximum future contingent payments           $ 60,000,000