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Equity-Based Compensation - Narrative (Details)
$ / shares in Units, $ in Millions
1 Months Ended 12 Months Ended
May 31, 2015
shares
Dec. 31, 2016
USD ($)
plan
$ / shares
shares
Dec. 31, 2015
USD ($)
$ / shares
Dec. 31, 2014
USD ($)
$ / shares
Nov. 30, 2014
shares
Equity compensation plans          
Number of equity compensation plans | plan   4      
Compensation cost not yet recognized | $   $ 37.7      
Options granted in period (USD per share) | $ / shares   $ 10.63 $ 23.57 $ 10.63  
Options vested in period (shares)   822,775      
Value of options exercised in period | $   $ 1.5 $ 31.2 $ 5.9  
Stock Options          
Equity compensation plans          
Compensation cost not yet recognized | $   $ 21.1      
Compensation cost not yet recognized for period   2 years 6 months      
RSUs          
Equity compensation plans          
Compensation cost not yet recognized | $   $ 16.6      
Compensation cost not yet recognized for period   1 year 9 months 18 days      
RSUs granted (USD per share) | $ / shares   $ 22.28 $ 52.71 $ 22.88  
Value of RSUs vested during period | $   $ 9.1 $ 3.5 $ 2.7  
2007 Equity Plan | Stock Options          
Equity compensation plans          
Remaining number of shares available for future grants (shares)   1,786,672      
Shares authorized for issuance (shares)   6,995,325      
2007 Equity Plan | Stock Options | Minimum          
Equity compensation plans          
Offering period term (years)   7 years      
2007 Equity Plan | Stock Options | Maximum          
Equity compensation plans          
Offering period term (years)   10 years      
2000 Equity Plan          
Equity compensation plans          
Remaining number of shares available for future grants (shares)   0      
2000 Equity Plan | Stock Options          
Equity compensation plans          
Offering period term (years)   10 years      
2013 Lumara Equity Plan | Stock Options          
Equity compensation plans          
Remaining number of shares available for future grants (shares)   9,710      
Shares authorized for issuance (shares)         200,000
Offering period term (years)   10 years      
2015 ESPP | Stock Options          
Equity compensation plans          
Shares authorized for issuance (shares) 200,000        
Offering period term (years) 6 months        
Annual maximum percentage of employee compensation available for ESPP share purchases (percent) 10.00%        
Purchase price per share as a percentage of fair market value of common stock on the first or last day of the plan period (percent) 85.00%        
Shares issued (shares)   79,324      
Inducement Grants | Stock Options          
Equity compensation plans          
Award vesting period (years)   4 years      
Inducement Grants | RSUs          
Equity compensation plans          
Award vesting period (years)   3 years