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Fair Value Measurements - Contingent Consideration (Details) - USD ($)
3 Months Ended 9 Months Ended
Jun. 30, 2016
Sep. 30, 2016
Sep. 30, 2015
Reconciliation of contingent consideration obligations related to acquisitions      
Adjustments to fair value of contingent consideration   $ 5,106,000 $ 4,525,000
Change in fair value of contingent consideration   5,106,000 $ 4,525,000
Lumara Health and MuGard Rights | Fair Value, Measurements, Recurring | Significant Unobservable Inputs (Level 3)      
Reconciliation of contingent consideration obligations related to acquisitions      
Balance at beginning of period   222,559,000  
Payments made   (212,000)  
Adjustments to fair value of contingent consideration   5,106,000  
Balance at end of period   227,453,000  
Change in fair value of contingent consideration   5,106,000  
Mekana      
Acquired Finite-Lived Intangible Assets [Line Items]      
Contingent consideration classified as short-term liability   100,000,000  
Reconciliation of contingent consideration obligations related to acquisitions      
Adjustments to fair value of contingent consideration   10,200,000  
Change in fair value of contingent consideration   10,200,000  
Milestone payment expected to be paid in 2016 to the former Lumara Health security holders based on achievement of a net sales milestone of Makena   $ 100,000,000  
Discount rate (as a percent)   5.00%  
Estimated undiscounted milestone amounts payable   $ 350,000,000  
MuGard      
Acquired Finite-Lived Intangible Assets [Line Items]      
Contingent consideration classified as short-term liability   400,000  
Reconciliation of contingent consideration obligations related to acquisitions      
Adjustments to fair value of contingent consideration $ (5,600,000) (5,100,000)  
Change in fair value of contingent consideration $ (5,600,000) $ (5,100,000)  
Discount rate (as a percent)   9.00%  
Period over which estimated undiscounted royalty amounts could be paid   10 years  
MuGard | Minimum      
Reconciliation of contingent consideration obligations related to acquisitions      
Estimated undiscounted royalty amounts payable   $ 2,000,000  
MuGard | Maximum      
Reconciliation of contingent consideration obligations related to acquisitions      
Estimated undiscounted royalty amounts payable   6,000,000  
CBR      
Acquired Finite-Lived Intangible Assets [Line Items]      
Contingent consideration classified as short-term liability   $ 0