CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Sep. 30, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 305,279	$ 228,705
Investments	308,792	237,626
Accounts receivable, net	70,079	85,678
Inventories	38,157	40,645
Receivable from collaboration	0	428
Prepaid and other current assets	14,474	13,592
Total current assets	736,781	606,674
Property, plant and equipment, net	25,255	28,725
Goodwill	639,484	639,188
Intangible assets, net	1,122,535	1,196,771
Restricted cash	2,593	2,593
Other long-term assets	1,005	2,259
Total assets	2,527,653	2,476,210
Current liabilities:
Accounts payable	4,742	4,906
Accrued expenses	126,363	106,363
Current portion of long-term debt	62,791	17,500
Current portion of acquisition-related contingent consideration	100,359	96,967
Deferred revenues	34,653	20,185
Total current liabilities	328,908	245,921
Long-term liabilities:
Long-term debt, net	747,869	803,669
Convertible 2.5% notes, net	177,146	170,749
Acquisition-related contingent consideration	127,094	125,592
Deferred tax liabilities	192,608	189,145
Deferred revenues	12,513	5,093
Other long-term liabilities	3,562	3,777
Total liabilities	1,589,700	1,543,946
Commitments and contingencies
Stockholders’ equity:
Preferred stock, par value $0.01 per share, 2,000,000 shares authorized; none issued	0	0
Common stock, par value $0.01 per share, 117,500,000 shares authorized; 34,209,212 and 34,733,117 shares issued and outstanding at September 30, 2016 and December 31, 2015, respectively	342	347
Additional paid-in capital	1,230,595	1,233,786
Accumulated other comprehensive loss	(3,394)	(4,205)
Accumulated deficit	(289,590)	(297,664)
Total stockholders’ equity	937,953	932,264
Total liabilities and stockholders’ equity	$ 2,527,653	$ 2,476,210