UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A INFORMATION

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The Spectranetics Corporation

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The Spectranetics Corporation

9965 Federal Drive

Colorado Springs, Colorado 80921

SUPPLEMENT TO THE PROXY STATEMENT

FOR THE 2014 ANNUAL MEETING OF STOCKHOLDERS

TO BE HELD ON JUNE 10, 2014

The following information supplements and amends the proxy statement (the “Proxy Statement”) of The Spectranetics Corporation (“we,” “us,” “our,” or the “Company”) furnished to stockholders of the Company in connection with the solicitation of proxies by the Board of Directors (the “Board”) of the Company for the 2014 Annual Meeting of Stockholders (the “Annual Meeting”). This Supplement is being filed with the Securities and Exchange Commission (the “SEC”) and is being made available to stockholders on or about June 3, 2014.

THIS SUPPLEMENT CONTAINS IMPORTANT ADDITIONAL INFORMATION AND SHOULD BE READ IN CONJUNCTION WITH THE PROXY STATEMENT.

The following supplemental disclosure pertains to Proposal No. 4 in the Proxy Statement that the stockholders of the Company approve an amendment to the Company’s Amended and Restated Certificate of Incorporation (the “Certificate”) to increase the number of authorized shares of common stock to 120,000,000 shares and the number of authorized shares of capital stock to 125,000,000 shares. This information is in addition to the information required to be provided to the Company’s stockholders under the applicable proxy disclosure rules.

Supplemental Disclosure Regarding Proposal No. 4

As described in the Proxy Statement, our Board believes that it is desirable to increase the number of authorized shares of our common stock to provide us with adequate flexibility for future growth, strategic planning and general corporate activities.

On June 3, 2014, we issued $230 million aggregate principal amount of 2.625% Convertible Senior Notes due 2034 (the “Notes”) in an underwritten public offering. We are reserving approximately 7.3 million shares (the “Conversion Shares”) of our common stock for issuance upon the conversion of the Notes.

In the Proxy Statement, we explained that, as of March 31, 2014, we had approximately 14.3 million shares of authorized but unissued and unreserved common stock available for issuance. Because of the issuance of the Notes and the reservation of the Conversion Shares, we only have approximately 7.0 million shares of authorized but unissued and unreserved common stock available for issuance. In addition, if our stockholders approve Proposal No. 5 in the Proxy Statement to amend and restate our Amended and Restated 2006 Incentive Award Plan, the number of shares of common stock authorized for issuance under such plan will be increased by 2.9 million shares and the number of shares of our common stock authorized but unissued and unreserved for issuance will be further reduced to approximately 4.1 million shares.

Based on the foregoing, our Board believes that the proposal to amend the Company’s Certificate to increase the number of authorized shares of common stock and capital stock by 60,000,000 shares, as described in Proposal No. 4 in the Proxy Statement, is appropriate and beneficial to us because (i) following the issuance of the Notes, we will have very few authorized but unissued and unreserved shares of common stock and (ii) we will need additional authorized shares of common stock available for a variety of corporate purposes, including acquisitions, public or private offerings of common stock and other corporate financings, stock dividends, stock splits, strategic relationships with corporate partners and other investment opportunities, issuances of stock-based compensation and other corporate purposes that our Board deems advisable.

THE BOARD OF DIRECTORS UNANIMOUSLY RECOMMENDS A VOTE “FOR” PROPOSAL NO. 4.