CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Revenues:
License fee revenue	$ 0	$ 0	$ 0	$ 2,500
Collaboration revenue	0	0	0	59
Royalty revenue	73	83	347	226
Product sales, net	0	0	0	107
Total revenues, net	73	83	347	2,892
Cost and expenses:
Cost of sales	0	0	0	128
Research and development	549	1,077	1,676	2,808
Selling, marketing, general and administrative	543	1,068	2,332	3,427
Total cost and expenses	1,092	2,145	4,008	6,363
Operating loss	(1,019)	(2,062)	(3,661)	(3,471)
Interest expense, net (Note 8)	(76)	(138)	(189)	(473)
Loss before income taxes	(1,095)	(2,200)	(3,850)	(3,944)
Provision for income taxes	0	0	0	0
Net loss	$ (1,095)	$ (2,200)	$ (3,850)	$ (3,944)
Loss per share:
Basic	$ (0.05)	$ (0.12)	$ (0.18)	$ (0.27)
Diluted	$ (0.05)	$ (0.12)	$ (0.18)	$ (0.27)
Weighted average shares outstanding:
Basic	21,168	16,686	21,101	14,147
Diluted	21,168	16,686	21,101	14,147