Exhibit 8


                                POWER OF ATTORNEY

     KNOW ALL  PERSONS  BY THESE  PRESENTS,  that each  person  whose  signature
appears below  constitutes  and appoints  DAVID R. RAMSAY as his or her true and
lawful   attorney-in-fact  and  agents  with  full  power  of  substitution  and
resubstitution,  for him or her and in his or her name,  place and stead, in any
and all  capacities  to sign the  Schedule  13D  filed  herewith  and any or all
amendments  to said  Schedule  13D,  and to file the  same,  with  all  exhibits
thereto,  and other documents in connection  therewith,  with the Securities and
Exchange Commission granting unto said attorney-in-fact and agent the full power
and  authority  to do and  perform  each and every act and thing  requisite  and
necessary  to be done in and about the  foregoing,  as full to all  intents  and
purposes  as he or she  might  or  could  do in  person,  hereby  ratifying  and
confirming all that said  attorney-in-fact  and agent, or his or her substitute,
may lawfully do or cause to be done by virtue thereof.

     Pursuant to the  requirements  of the  Securities  Exchange Act of 1934, as
amended,  this  Schedule  13D has been  signed by the  following  persons in the
capacities and on the dates indicated.

Signature                  Title                               Date

/s/ Jan Leschly            Member, Care Capital II, LLC        December 30, 2002
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Name: Jan Leschly


/s/ Jerry N. Karabelas     Member, Care Capital II, LLC        December 30, 2002
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Name: Jerry N. Karabelas