Exhibit 22.1

Subsidiary Guarantors and Issuers of Guaranteed Securities and Affiliates Whose Securities Collateralize Securities of the Registrant

The entities listed in the table below are either direct or indirect subsidiaries of Encompass Health Corporation, and they each, jointly and severally, guarantee the payment of each series of unsecured senior notes issued by Encompass Health Corporation. There are no other outstanding debt securities of Encompass Health Corporation or its subsidiaries.

Subsidiaries of Encompass Health Corporation

A&B Home Health Solutions, LLC

Abba Home Health, L.P.

Advanced Homecare Holdings, Inc.

Advanced Homecare Management, Inc.

AHM Action Home Health, LP

AHM Texas GP, LLC

AHM Texas LP, Inc.

Apex Hospice LLC

Best Home Care LP

Camellia Home Health of Alabama, LLC

Camellia Home Health of East Tennessee, LLC

Camellia Home Health of the Gulf Coast, LLC

Camellia Hospice of Central Mississippi, LLC

Camellia Hospice of East Louisiana, LLC

Camellia Hospice of Louisiana, LLC

Camellia Hospice of North Mississippi, LLC

Camellia Hospice of Northeast Alabama LLC

Camellia Hospice of Northeast Mississippi, LLC

Camellia Hospice of South Alabama, LLC

Camellia Hospice of Southwest Mississippi, LLC

Camellia Hospice of the Gulf Coast, LLC

Camellia Medical Systems, Inc.

CareServices of the Treasure Coast, LLC

CareSouth Health System, Inc.

CareSouth HHA Holdings of Columbus, LLC

CareSouth HHA Holdings of Dothan, LLC

CareSouth HHA Holdings of Gainesville, LLC

CareSouth HHA Holdings of Greensboro, LLC

CareSouth HHA Holdings of Lexington, LLC

CareSouth HHA Holdings of North Florida, LLC

CareSouth HHA Holdings of Panama City, LLC

CareSouth HHA Holdings of Richmond, LLC

CareSouth HHA Holdings of South Carolina, LLC

CareSouth HHA Holdings of Tallahassee, LLC

CareSouth HHA Holdings of the Bay Area, LLC

CareSouth HHA Holdings of Valley, LLC

CareSouth HHA Holdings of Virginia, LLC

CareSouth HHA Holdings of Washington, LLC

CareSouth HHA Holdings of Western Carolina, LLC

CareSouth HHA Holdings of Winchester, LLC

CareSouth HHA Holdings, LLC

CareSouth Hospice, LLC

Continental Home Care, LLC

Continental Medical Systems, LLC

Continental Rehabilitation Hospital of Arizona, Inc.

CS Health & Wellness, LLC

Day-By-Day Staff Relief, LLC

DOSIK, INC.

DRC Health Systems, L.P.

EH Health Home Health of Alabama, LLC

EH Health Home Health of Birmingham, LLC

EH Health Home Health of Central Virginia, LLC

EH Health Home Health of Florida, LLC

EH Health Home Health of Kentucky, LLC

EH Health Home Health of New England, LLC

EH Health Home Health of Ohio, LLC

EH Health Home Health of the Northwest, LLC

EH Health Home Health of the Southwest, LLC

EH Health Hospice of Alabama, LLC

EH Health Hospice of Pennsylvania, LLC

EH Health Hospice of the Midwest, LLC

EH Health Hospice of the Northwest, LLC

EH Health Hospice of the Southwest, LLC

EH Health Ventures Bozeman, LLC

EH Health Ventures Salida, LLC

EH Home Health of Austin, LLC

EH Home Health of Colorado, LLC

EH Home Health of DFW, LLC

EH Home Health of East Texas, LLC

EH Home Health of New England, LLC

EH Home Health of the Mid Atlantic, LLC

EH Home Health of the Midwest, LLC

EH Home Health of the Southeast, LLC

EH Home Health of the West, LLC

EH Hospice of the West, LLC

EH of Fort Worth, LP

EH of West Texas, LP

EHHI Holdings, Inc.

Encompass Health Acquisition Holdings Subsidiary, LLC

Encompass Health Acquisition Holdings, LLC

Encompass Health Alabama Real Estate, LLC

Encompass Health Arizona Real Estate, LLC

Encompass Health Arkansas Real Estate, LLC

Encompass Health Boise Holdings, LLC

Encompass Health Bryan Holdings, LLC

Encompass Health C Corp Sub Holdings, Inc.

Encompass Health California Real Estate, LLC

Encompass Health Central Arkansas Holdings, Inc.

Encompass Health Charleston Holdings, LLC

Encompass Health Colorado Real Estate, LLC

Encompass Health Dayton Holdings, LLC

Encompass Health Deaconess Holdings, LLC

Encompass Health Fairlawn Holdings, LLC

Encompass Health GKBJH Holdings, LLC

Encompass Health Gulfport Holdings, LLC

Encompass Health Home Health Corporation

Encompass Health Home Health Holdings, Inc.

Encompass Health Iowa City Holdings, LLC

Encompass Health Iowa Real Estate, LLC

Encompass Health Johnson City Holdings, LLC

Encompass Health Joint Ventures Holdings, LLC

Encompass Health Jonesboro Holdings, Inc.

Encompass Health Kansas Real Estate, LLC

Encompass Health Kentucky Real Estate, LLC

Encompass Health Kingsport Holdings, LLC

Encompass Health Littleton Holdings, LLC

Encompass Health Louisiana Real Estate, LLC

Encompass Health Lubbock Holdings, LLC

Encompass Health Martin County Holdings, LLC

Encompass Health Maryland Real Estate, LLC

Encompass Health Massachusetts Real Estate, LLC

Encompass Health Midland Odessa Holdings, LLC

Encompass Health Myrtle Beach Holdings, LLC

Encompass Health Nevada Real Estate, LLC

Encompass Health New Mexico Real Estate, LLC

Encompass Health Ohio Real Estate, LLC

Encompass Health Owned Hospitals Holdings, LLC

Encompass Health Pennsylvania Real Estate, LLC

Encompass Health Properties, LLC

Encompass Health Real Estate, LLC

Encompass Health Rehabilitation Hospital of Abilene, LLC

Encompass Health Rehabilitation Hospital of Albuquerque, LLC

Encompass Health Rehabilitation Hospital of Altamonte Springs, LLC

Encompass Health Rehabilitation Hospital of Arlington, LLC

Encompass Health Rehabilitation Hospital of Austin, LLC

Encompass Health Rehabilitation Hospital of Bakersfield, LLC

Encompass Health Rehabilitation Hospital of Bluffton, LLC

Encompass Health Rehabilitation Hospital of Braintree, LLC

Encompass Health Rehabilitation Hospital of Cardinal Hill, LLC

Encompass Health Rehabilitation Hospital of Cincinnati, LLC

Encompass Health Rehabilitation Hospital of City View, Inc.

Encompass Health Rehabilitation Hospital of Colorado Springs, Inc.

Encompass Health Rehabilitation Hospital of Columbia, Inc.

Encompass Health Rehabilitation Hospital of Concord, Inc.

Encompass Health Rehabilitation Hospital of Cypress, LLC

Encompass Health Rehabilitation Hospital of Dallas, LLC

Encompass Health Rehabilitation Hospital of Desert Canyon, LLC

Encompass Health Rehabilitation Hospital of Dothan, Inc.

Encompass Health Rehabilitation Hospital of East Valley, LLC

Encompass Health Rehabilitation Hospital of Erie, LLC

Encompass Health Rehabilitation Hospital of Florence, Inc.

Encompass Health Rehabilitation Hospital of Fort Smith, LLC

Encompass Health Rehabilitation Hospital of Franklin, LLC

Encompass Health Rehabilitation Hospital of Fredericksburg, LLC

Encompass Health Rehabilitation Hospital of Gadsden, LLC

Encompass Health Rehabilitation Hospital of Greenville, LLC

Encompass Health Rehabilitation Hospital of Harmarville, LLC

Encompass Health Rehabilitation Hospital of Henderson, LLC

Encompass Health Rehabilitation Hospital of Humble, LLC

Encompass Health Rehabilitation Hospital of Katy, LLC

Encompass Health Rehabilitation Hospital of Lakeview, LLC

Encompass Health Rehabilitation Hospital of Largo, LLC

Encompass Health Rehabilitation Hospital of Las Vegas, LLC

Encompass Health Rehabilitation Hospital of Littleton, LLC

Encompass Health Rehabilitation Hospital of Manati, Inc.

Encompass Health Rehabilitation Hospital of Mechanicsburg, LLC

Encompass Health Rehabilitation Hospital of Miami, LLC

Encompass Health Rehabilitation Hospital of Middletown, LLC

Encompass Health Rehabilitation Hospital of Modesto, LLC

Encompass Health Rehabilitation Hospital of Montgomery, Inc.

Encompass Health Rehabilitation Hospital of Murrieta, LLC

Encompass Health Rehabilitation Hospital of New England, LLC

Encompass Health Rehabilitation Hospital of Nittany Valley, Inc.

Encompass Health Rehabilitation Hospital of North Tampa, LLC

Encompass Health Rehabilitation Hospital of Northern Kentucky, LLC

Encompass Health Rehabilitation Hospital of Northern Virginia, LLC

Encompass Health Rehabilitation Hospital of Northwest Tucson, L.P.

Encompass Health Rehabilitation Hospital of Ocala, LLC

Encompass Health Rehabilitation Hospital of Panama City, Inc.

Encompass Health Rehabilitation Hospital of Pearland, LLC

Encompass Health Rehabilitation Hospital of Pensacola, LLC

Encompass Health Rehabilitation Hospital of Petersburg, LLC

Encompass Health Rehabilitation Hospital of Plano, LLC

Encompass Health Rehabilitation Hospital of Reading, LLC

Encompass Health Rehabilitation Hospital of Richardson, LLC

Encompass Health Rehabilitation Hospital of Round Rock, LLC

Encompass Health Rehabilitation Hospital of San Antonio, Inc.

Encompass Health Rehabilitation Hospital of San Juan, Inc.

Encompass Health Rehabilitation Hospital of Sarasota, LLC

Encompass Health Rehabilitation Hospital of Scottsdale, LLC

Encompass Health Rehabilitation Hospital of Shelby County, LLC

Encompass Health Rehabilitation Hospital of Shreveport, LLC

Encompass Health Rehabilitation Hospital of Sioux Falls, LLC

Encompass Health Rehabilitation Hospital of Spring Hill, Inc.

Encompass Health Rehabilitation Hospital of Sugar Land, LLC

Encompass Health Rehabilitation Hospital of Sunrise, LLC

Encompass Health Rehabilitation Hospital of Tallahassee, LLC

Encompass Health Rehabilitation Hospital of Texarkana, Inc.

Encompass Health Rehabilitation Hospital of the Mid-Cities, LLC

Encompass Health Rehabilitation Hospital of The Woodlands, Inc.

Encompass Health Rehabilitation Hospital of Toledo, LLC

Encompass Health Rehabilitation Hospital of Toms River, LLC

Encompass Health Rehabilitation Hospital of Treasure Coast, Inc.

Encompass Health Rehabilitation Hospital of Tustin, L.P.

Encompass Health Rehabilitation Hospital of Utah, LLC

Encompass Health Rehabilitation Hospital of Vineland, LLC

Encompass Health Rehabilitation Hospital of Waco, LLC

Encompass Health Rehabilitation Hospital of Western Massachusetts, LLC

Encompass Health Rehabilitation Hospital of York, LLC

Encompass Health Rehabilitation Hospital The Vintage, LLC

Encompass Health Rehabilitation Hospital Vision Park, LLC

Encompass Health Rehabilitation Institute of Tucson, LLC

Encompass Health San Angelo Holdings, LLC

Encompass Health Savannah Holdings, LLC

Encompass Health Sea Pines Holdings, LLC

Encompass Health Sewickley Holdings, LLC

Encompass Health South Carolina Real Estate, LLC

Encompass Health South Dakota Real Estate, LLC

Encompass Health Support Companies, LLC

Encompass Health Texas Real Estate, LLC

Encompass Health Tucson Holdings, LLC

Encompass Health Tulsa Holdings, LLC

Encompass Health Tyler Holdings, Inc.

Encompass Health Utah Real Estate, LLC

Encompass Health ValleyofTheSun Rehabilitation Hospital, LLC

Encompass Health Virginia Real Estate, LLC

Encompass Health Walton Rehabilitation Hospital, LLC

Encompass Health West Tennessee Holdings, LLC

Encompass Health West Virginia Real Estate, LLC

Encompass Health Westerville Holdings, LLC

Encompass Health Winston-Salem Holdings, LLC

Encompass Health Yuma Holdings, Inc.

EXCELLA ASSOCIATES, L.L.C.

EXCELLA HEALTHCARE, INC.

EXCELLA HOME HEALTH AGENCY, LLC

EXCELLA HOMECARE, INC.

Guardian Home Care, Inc.

Hallmark Homecare, L.P.

HealthCare Innovations of Oklahoma, L.L.C.

HEALTHCARE INNOVATIONS OF WESTERN OKLAHOMA, LLC

HealthCare Innovations-Travertine Health Services, L.L.C.

HealthSouth Rehabilitation Hospital of Austin, Inc.

HealthSouth Rehabilitation Hospital of Forsyth County, LLC

HealthSouth Rehabilitation Hospital of Fort Worth, LLC

Home Health Care of Bogalusa, Inc.

Home Health Care Systems, Inc.

Hospice Care of Mississippi, LLC

Idaho Homecare Holdings, Inc.

Orion Homecare, LLC

Preferred Home Health, L.P.

Print Promotions Group, LLC

Rebound, LLC

Rehabilitation Hospital Corporation of America, LLC

Rehabilitation Hospital of North Alabama, LLC

Rehabilitation Hospital of Plano, LLC

Reliant Blocker Corp.

Saad Healthcare of St. Clair County LLC

Texas Senior Care, L.P.

TH of San Antonio LLC

WellCare, Inc.

Wellmark Healthcare Services of El Paso, Inc.

West Mississippi Home Health Services, Inc.

Western Neuro Care, Inc.