Exhibit 12.1

CryoLife, Inc.

Ratio (Deficiency) of Earnings to Fixed Charges

(in thousands)

	For the year ended December 31,										Six Months Ended June 30,
	2010		2011		2012		2013		2014		2015
“Earnings” per Item 503(d) Reg S-K
Pretax income (loss)		7,277		11,466		12,052		23,292		8,703		(1,607	)
Fixed Charges:
Interest Expense		180		142		179		71		175		60
Capitalized Interest		—		—		—		—		—		—
Amort prem, disc, and expenses of debt		143		109		103		139		160		75
Interest within rental expense		852		893		908		998		1,016		563
Total Fixed Charges		1,175		1,144		1,190		1,208		1,351		698
Preferred dividends		—		—		—		—		—		—
Gross up of preferred dividends		—		—		—		—		—		—
Total fixed charges and dividends		1,175		1,144		1,190		1,208		1,351		698
Amort. of Capitalized Interest		58		58		58		58		58		29
Total “Earnings”		8,510		12,668		13,300		24,558		10,112		(880	)
Less Capitalized Interest		—		—		—		—		—		—
Adjusted “Earnings”		8,510		12,668		13,300		24,558		10,112		(880	)
Income tax benefit (expense)		—		—		—		—		—		—
Ratio of Earnings to Fixed Charges		7.24		11.07		11.18		20.33		7.48		N/A
Deficiency of Earnings to Fixed Charges		N/A		N/A		N/A		N/A		N/A		(1,578	)
Ratio of Earnings to Fixed Charges and Preferred Dividends		7.24		11.07		11.18		20.33		7.48		N/A
Deficiency of Earnings Available to Cover Fixed Charges and Preferred Dividends		N/A		N/A		N/A		N/A		N/A		(1,578	)