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PerClot Technology Acquisition (Details) (USD $)
12 Months Ended 0 Months Ended 3 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2011
PerClot [Member]
Sep. 28, 2010
PerClot [Member]
Trademarks [Member]
Sep. 28, 2010
PerClot [Member]
Distribution And Manufacturing Right In Certain International Countries [Member]
Sep. 28, 2010
Starch Technology Purchase [Member]
Sep. 30, 2010
Starch Technology Purchase [Member]
Business Acquisition [Line Items]                
Term of distribution agreement             15 years  
Option to purchase certain remaining related technology             3 years  
Cash paid for acquisition             $ 6,750,000  
Number of shares issued as consideration for PerClot technology acquisition             209,000  
Contingent payment             250,000  
Additional contingent amounts paid if FDA regulatory and other commercial milestones are achieved             2,500,000  
Initial aggregate consideration             8,000,000  
Approximate value of restricted common stock issued for acquisition             1,000,000  
Non-current assets for prepaid royalties             1,500,000  
Deferred tax asset             145,000  
Amortizable intangible assets         327,000 2,600,000 2,600,000  
In-process research and development               3,500,000
Intangible asset useful life 14 years           15 years  
Research and development 7,257,000 6,899,000 5,923,000 250,000        
Expected future contingent payment amounts to be initially recorded as research and development expense             $ 2,500,000