Exhibit 107

Calculation of Filing Fee Table

S-3

(Form Type)

Pfizer Inc.

Pfizer Investment Enterprises Pte. Ltd.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities and Carry Forward Securities

Security  Type

Security  Class  Title (4)

Fee Calculation or Carry Forward Rule

Amount  Registered

Proposed  Maximum  Offering  Price Per  Unit

Maximum  Aggregate  Offering  Price

Fee  Rate

Amount of  Registration  Fee

Carry  Forward  Form  Type

Carry  Forward  File  Number

Carry  Forward  Initial  Effective  Date

Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward

Newly Registered Securities

Debt

Debt  Securities of  Pfizer Inc.

Rule 456(b) and Rule 457(r)

(1) (2)

(1) (2)

(1) (2)

(3)

(3)

Equity

Common  Stock of  Pfizer Inc.,  $0.05 par  value

Rule 456(b) and Rule 457(r)

(1) (2)

(1) (2)

(1) (2)

(3)

(3)

Equity

Preferred  Stock of  Pfizer Inc.,  without par  value

Rule 456(b) and Rule 457(r)

(1) (2)

(1) (2)

(1) (2)

(3)

(3)

Other

Warrants of  Pfizer Inc.

Other (5)

(1) (2)

(1) (2)

(1) (2)

(3)

(3)

Fees to be Paid

Equity

Depositary  Shares of  Pfizer Inc.

Rule 456(b) and Rule 457(r)

(1) (2)

(1) (2)

(1) (2)

(3)

(3)

Other

Purchase  Contracts of  Pfizer Inc.

Rule 456(b) and Rule 457(r)

(1) (2)

(1) (2)

(1) (2)

(3)

(3)

Other

Purchase  Units of  Pfizer Inc.

Rule 456(b) and Rule 457(r)

(1) (2)

(1) (2)

(1) (2)

(3)

(3)

Other

Guarantees  of Pfizer Inc.

Other (6)

(1) (2)

(1) (2)

(1) (2)

(3)

(3)

Debt

Debt  Securities of  Pfizer  Investment  Enterprises  Pte. Ltd.

Rule 456(b) and Rule 457(r)

(1) (2)

(1) (2)

(1) (2)

(3)

(3)

Fees Previously Paid

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Carry Forward Securities

Carry Forward Securities

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Total Offering Amounts

N/A

N/A

Total Fees Previously Paid

N/A

Total Fee Offsets

N/A

Net Fee Due

N/A

(1) Omitted pursuant to Form S-3 Instructions to the Calculation of Filing Fee Tables and Related Disclosure 2.A.iii.c

(2) An indeterminate aggregate initial offering price, principal amount or number of the securities of each identified class is being registered as may from time to time be offered at indeterminate prices or upon conversion, exchange or exercise of other securities. Separate consideration may or may not be received for securities that are issuable on exercise, conversion or exchange of other securities.

(3) In accordance with Rule 456(b) and Rule 457(r) under the Securities Act of 1933, as amended, the Registrants are deferring payment of all of the registration fee. Any subsequent registration fees will be paid on a pay-as-you-go basis. The Registrants will calculate the registration fee applicable to an offer of securities pursuant to this Registration Statement based on the fee payment rate in effect on the date of such fee payment.

(4) Any securities registered hereunder may be sold separately or as units with other securities registered hereunder.

(5) Pursuant to Rule 457(g) under the Securities Act of 1933, as amended, no separate registration fee is required with respect to the warrants.

(6) Pursuant to Rule 457(n) under the Securities Act of 1933, as amended, no additional registration fee is required with respect to the guarantees.