Exhibit 12

PFIZER INC. AND SUBSIDIARY COMPANIES

COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES

	Year Ended December 31,
(millions except ratios)	2010		2009		2008		2007		2006
Determination of Earnings:
Income from continuing operations before provision for taxes on income, noncontrolling interests and cumulative effect of a change in accounting principles	$	9,422	$	10,827	$	9,694	$	9,278	$	13,028
Less:
Noncontrolling interests		32		9		23		42		12
Income attributable to Pfizer Inc.		9,390		10,818		9,671		9,236		13,016
Add:
Fixed charges		1,936		1,361		647		541		642
Total earnings as defined	$	11,326	$	12,179	$	10,318	$	9,777	$	13,658
Fixed charges:
Interest expense (a)	$	1,799	$	1,233	$	516	$	397	$	488
Preferred stock dividends (b)		6		7		8		11		14
Rents (c)		131		121		123		133		140
Fixed charges		1,936		1,361		647		541		642
Capitalized interest		36		34		46		43		29
Total fixed charges	$	1,972	$	1,395	$	693	$	584	$	671
Ratio of earnings to fixed charges		5.7		8.7		14.9		16.7		20.4

(a) Interest expense includes amortization of debt premium, discount and expenses. Interest expense does not include interest related to uncertain tax positions of $384 million for 2010; $337 million for 2009; $333 million for 2008; $331 million for 2007 and $200 million for 2006.

(b) Preferred stock dividends are from our Series A convertible perpetual preferred stock held by an Employee Stock Ownership Plan assumed in connection with our acquisition of Pharmacia in 2003.

(c) Rents included in the computation consist of one-third of rental expense which we believe to be a conservative estimate of an interest factor in our leases, which are not material.