Pension and Postretirement Benefit Plans and Defined Contribution Plans - Obligations and Funded Status (Details) - USD ($) $ in Millions		12 Months Ended
		Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Amounts recorded in our consolidated balance sheet:
Noncurrent liabilities		$ (2,250)	$ (3,724)
Pension Plan [Member] | Group Annuity Contract [Member]
Change in benefit obligation
Benefit obligation, ending		586
Change in plan assets
Fair value, ending		588
Postretirement Benefits Plan [Member]
Change in benefit obligation
Benefit obligation, beginning	[1]	995	1,238
Service cost		29	36	$ 38
Interest cost		27	29	49
Employee contributions		75	78
Plan amendments		24	(116)
Changes in actuarial assumptions and other	[2]	(593)	(117)
Foreign exchange impact		(5)	1
Upjohn spin-off	[3]	0	0
Acquisitions/divestitures, net		0
Curtailments and special termination benefits		(3)	(8)
Settlements	[4]	(39)	0
Benefits paid		(101)	(147)
Benefit obligation, ending	[1]	410	995	1,238
Change in plan assets
Fair value, beginning		753	588
Actual return on plan assets		(106)	89
Company contributions		65	145
Employee contributions		75	78
Foreign exchange impact		0	0
Upjohn spin-off	[3]	0	0
Acquisitions/divestitures, net		0	0
Settlements	[4]	(39)	0
Benefits paid		(101)	(147)
Fair value, ending		647	753	588
Funded status		238	(241)
Amounts recorded in our consolidated balance sheet:
Noncurrent assets		322	0
Current liabilities		(6)	(6)
Noncurrent liabilities		(78)	(235)
Funded status		238	(241)
Pre-tax components of cumulative amounts recognized in Accumulated other comprehensive loss:
Prior service (costs)/credits		413	581
U.S. [Member] | Pension Plan [Member]
Change in benefit obligation
Benefit obligation, beginning	[1]	17,150	18,306
Service cost		0	0	0
Interest cost		534	455	533
Employee contributions		0	0
Plan amendments		0	0
Changes in actuarial assumptions and other	[2]	(4,187)	(331)
Foreign exchange impact		(1)	0
Upjohn spin-off	[3]	0	0
Acquisitions/divestitures, net		61	0
Curtailments and special termination benefits		18	17
Settlements	[4]	(1,698)	(785)
Benefits paid		(457)	(512)
Benefit obligation, ending	[1]	11,420	17,150	18,306
Change in plan assets
Fair value, beginning		16,346	16,094
Actual return on plan assets		(3,550)	1,405
Company contributions		230	143
Employee contributions		0	0
Foreign exchange impact		0	0
Upjohn spin-off	[3]	0	0
Acquisitions/divestitures, net		1
Settlements	[4]	(1,698)	(785)
Benefits paid		(457)	(512)
Fair value, ending		10,871	16,346	16,094
Funded status		(549)	(805)
Amounts recorded in our consolidated balance sheet:
Noncurrent assets		346	447
Current liabilities		(110)	(138)
Noncurrent liabilities		(785)	(1,113)
Funded status		(549)	(805)
Pre-tax components of cumulative amounts recognized in Accumulated other comprehensive loss:
Prior service (costs)/credits		(4)	(6)
Pension plans with an ABO in excess of plan assets:
Fair value of plan assets	[5]	86	120
ABO	[5]	981	1,371
Pension plans with a PBO in excess of plan assets:
Fair value of plan assets	[5]	86	120
PBO	[5]	981	1,371
U.S. [Member] | Postretirement Benefits Plan [Member]
Change in plan assets
Fair value, beginning	[6]	753
Fair value, ending	[6]	647	753
International [Member] | Pension Plan [Member]
Change in benefit obligation
Benefit obligation, beginning	[1]	11,657	12,001
Service cost		116	130	146
Interest cost		157	146	164
Employee contributions		9	10
Plan amendments		0	0
Changes in actuarial assumptions and other	[2]	(2,931)	89
Foreign exchange impact		(1,065)	(298)
Upjohn spin-off	[3]	37	3
Acquisitions/divestitures, net		(50)	0
Curtailments and special termination benefits		(10)	(2)
Settlements	[4]	(64)	(47)
Benefits paid		(359)	(374)
Benefit obligation, ending	[1]	7,497	11,657	12,001
Change in plan assets
Fair value, beginning		10,729	9,811
Actual return on plan assets		(2,624)	1,106
Company contributions		156	451
Employee contributions		9	10
Foreign exchange impact		(1,037)	(229)
Upjohn spin-off	[3]	45	2
Acquisitions/divestitures, net		9
Settlements	[4]	(64)	(47)
Benefits paid		(359)	(374)
Fair value, ending		6,865	10,729	$ 9,811
Funded status		(632)	(928)
Amounts recorded in our consolidated balance sheet:
Noncurrent assets		783	1,480
Current liabilities		(27)	(33)
Noncurrent liabilities		(1,388)	(2,376)
Funded status		(632)	(928)
Pre-tax components of cumulative amounts recognized in Accumulated other comprehensive loss:
Prior service (costs)/credits		(34)	(35)
Pension plans with an ABO in excess of plan assets:
Fair value of plan assets	[5]	343	1,304
ABO	[5]	1,600	3,344
Pension plans with a PBO in excess of plan assets:
Fair value of plan assets	[5]	1,081	1,381
PBO	[5]	2,496	3,789
Defined benefit plan, accumulated benefit obligation		$ 7,200	$ 11,200

[1] For the U.S. pension plans, the benefit obligation is both the PBO and ABO as these plans are frozen and future benefit accruals no longer increase with future compensation increases. For the international pension plans, the benefit obligation is the PBO. The ABO for our international pension plans was $7.2 billion in 2022 and $11.2 billion in 2021. For the postretirement plans, the benefit obligation is the ABO.

[2] For both 2022 and 2021, primarily includes actuarial gains resulting from increases in discount rates, offset by increases in inflation assumptions for the international plan.

[3] For more information, see Note 2B.

[4] As a result of a group annuity contract entered into between Pfizer and a third party insurance company in July 2022, the third party insurance company assumed future benefit obligations and responsibility for the annuity payments of certain retirees in the Pfizer Consolidated Pension Plan. As of December 31, 2022, $586 million of benefit obligations and $588 million of plan assets are associated with this contract. We expect to finalize the remaining regulatory approvals for this transaction in due course.

[5] Our main U.S. qualified plan, U.S. postretirement plan and many of our international plans were overfunded as of December 31, 2022.

[6] Reflects postretirement plan assets, which support a portion of our U.S. retiree medical plans.