Acquisitions, Divestitures, Equity-Method Investments, Licensing Arrangements and Collaborative Arrangements - Licensing Arrangements (Details) - Valneva [Member] - Licensing Agreements [Member] € in Millions, $ in Millions			1 Months Ended	3 Months Ended	24 Months Ended
	Dec. 31, 2022	Apr. 30, 2020 USD ($)	Jun. 30, 2022 USD ($)	Jun. 28, 2020 USD ($)	Dec. 31, 2022 USD ($)	Jun. 30, 2022 EUR (€)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum potential consideration		$ 308
Potential early commercialization milestones		$ 143
Development cost ownership percentage		30.00%	40.00%
Investment amount			$ 95			€ 90.5
Tiered royalties		19.00%
Potential cumulative sales milestones			$ 100
Ownership percentage	6.90%
Acquired In-Process Research and Development Expense [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Payment for licensing arrangement				$ 130	$ 35
Minimum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Tiered royalties			14.00%
Maximum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Tiered royalties			22.00%