Segment, Geographic and Other Revenue Information - Narrative (Detail) $ in Millions	12 Months Ended
Dec. 31, 2022 USD ($) operatingSegment country	Dec. 31, 2021 USD ($) country	Dec. 31, 2020 country
Segment Reporting Information [Line Items]
Number of operating segments \| operatingSegment	2
Total assets	$ 197,205	$ 181,476
Remaining performance obligation	15,000
Deferred revenues, current	2,520	3,067
Government and Government Sponsored [Member] \| Comirnaty [Member]
Segment Reporting Information [Line Items]
Deferred revenues	2,500	3,300
Deferred revenues, current	2,400	3,000
Deferred revenues, noncurrent	77	$ 249
Deferred revenue, revenue recognized	$ 3,100
Geographic Concentration Risk [Member] \| Revenue [Member] \| Outside United States [Member]
Segment Reporting Information [Line Items]
Number of countries with revenue exceeding $500 million \| country	24	21	8
Geographic Concentration Risk [Member] \| Revenue [Member] \| U.S. [Member]
Segment Reporting Information [Line Items]
Concentration risk, percentage	10.00%	10.00%	10.00%
Geographic Concentration Risk [Member] \| Revenue [Member] \| Japan [Member]
Segment Reporting Information [Line Items]
Concentration risk, percentage	8.00%	9.00%	6.00%
Customer Concentration Risk [Member] \| Accounts Receivable [Member] \| Three Largest U.S. Wholesaler Customers [Member]
Segment Reporting Information [Line Items]
Concentration risk, percentage	32.00%	24.00%	30.00%
Customer Concentration Risk [Member] \| Revenue [Member] \| Government and Government Sponsored [Member]
Segment Reporting Information [Line Items]
Concentration risk, percentage	23.00%	13.00%
Credit Concentration Risk [Member] \| Accounts Receivable [Member] \| Government and Government Sponsored [Member]
Segment Reporting Information [Line Items]
Concentration risk, percentage	4.00%	12.00%

Concentration Risk, Revenues, $500,000,000 or More, Number of Countries

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Sum of the carrying amounts as of the balance sheet date of all assets that are recognized. Assets are probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.

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For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable, classified as noncurrent.

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