Acquisition, Discontinued Operations, Equity-Method Investment and Collaborative Arrangement - Acquisitions Narrative (Details) - USD ($) $ / shares in Units, $ in Millions			3 Months Ended	6 Months Ended
		Mar. 11, 2022	Apr. 03, 2022	Jul. 03, 2022	Jul. 04, 2021	Dec. 31, 2021
Business Acquisition [Line Items]
Payments to acquire businesses, net of cash acquired				$ 6,225	$ 0
Goodwill	[1]			$ 49,891		$ 49,208
Arena [Member]
Business Acquisition [Line Items]
Business acquisition, per share in cash (in dollars per share)		$ 100
Payments to acquire businesses, gross		$ 6,600
Payments to acquire businesses, net of cash acquired		6,200
Intangible assets acquired		5,500
Goodwill		1,000
Net deferred tax liabilities		510
Arena [Member] | Restructuring Charges And Acquisition-Related Costs [Member]
Business Acquisition [Line Items]
Post closing compensation expense		138	$ 138
IPR&D [Member] | Arena [Member]
Business Acquisition [Line Items]
Intangible assets acquired		5,000
Licensing Agreements and Other [Member] | Arena [Member]
Business Acquisition [Line Items]
Intangible assets acquired		$ 460

[1] All goodwill is assigned within the Biopharma reportable segment.