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Acquisitions, Divestitures, Equity-Method Investments and Assets and Liabilities Held for Sale, Licensing Arrangements and Research and Development and Collaborative Arrangements - Licensing Arrangements (Details) - Licensing Agreements [Member] - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Nov. 30, 2019
Sep. 30, 2018
Dec. 31, 2019
Sep. 30, 2018
Apr. 01, 2018
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Proceeds from licensing arrangement             $ 101  
Akcea And Ionis [Member] | Research and Development Expense [Member]                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Payment for licensing arrangement $ 250   $ 250          
Licensing arrangement, maximum potential milestones $ 1,300              
Shire [Member]                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Licensing arrangement, maximum potential milestones               $ 460
Proceeds from licensing arrangement       $ 35 $ 75 $ 110    
Shire [Member] | Other Nonoperating Income (Expense) [Member]                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Proceeds from licensing arrangement         $ 75     $ 90
BionTech [Member]                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Licensing arrangement, maximum potential milestones   $ 325            
BionTech [Member] | Research and Development Expense [Member]                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Payment for licensing arrangement   $ 50            
Long-term Investments [Member] | BionTech [Member]                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Number of shares purchased       169,670        
Value of shares purchased       $ 50