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Financial Instruments - Other Noncurrent Liabilities (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Apr. 30, 2018
Dec. 31, 2017
Aug. 31, 2017
Jun. 30, 2017
Sep. 30, 2018
Jul. 01, 2018
Dec. 31, 2018
Aug. 31, 2018
Jun. 30, 2018
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net   $ 36,562         $ 31,045    
Mylotarg [Member] | EU [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Research and development arrangement, aggregate payment obligation, term 10 years                
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement $ 301                
Bosulif [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Research and development arrangement, aggregate payment obligation, term             9 years    
Bosulif [Member] | United States [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Research and development arrangement, aggregate payment obligation, term   10 years              
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement   $ 416         $ 240    
Besponsa [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Research and development arrangement, aggregate payment obligation, term             8 years    
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement             $ 422    
Besponsa [Member] | EU [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Research and development arrangement, aggregate payment obligation, term       9 years          
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement       $ 148          
Besponsa [Member] | United States [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Research and development arrangement, aggregate payment obligation, term     9 years            
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement     $ 296            
Developed Technology Rights [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net [1]   34,765         30,535    
Developed Technology Rights [Member] | Mylotarg [Member] | EU [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net $ 240                
Lump sum payment for liability buyout                 $ 224
Non-cash gain from buyout transaction           $ 17 17    
Developed Technology Rights [Member] | Bosulif [Member] | United States [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net   $ 364         209    
Lump sum payment for liability buyout               $ 71  
Non-cash gain from buyout transaction         $ 9        
Developed Technology Rights [Member] | Besponsa [Member] | EU [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net       $ 123     122    
Developed Technology Rights [Member] | Besponsa [Member] | United States [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net     $ 248       243    
Other Noncurrent Liabilities [Member] | Developed Technology Rights [Member] | Bosulif [Member] | United States [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net             186    
Other Noncurrent Liabilities [Member] | Developed Technology Rights [Member] | Besponsa [Member] | EU [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net             119    
Other Noncurrent Liabilities [Member] | Developed Technology Rights [Member] | Besponsa [Member] | United States [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net             235    
Other current liabilities [Member] | Developed Technology Rights [Member] | Bosulif [Member] | United States [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net             23    
Other current liabilities [Member] | Developed Technology Rights [Member] | Besponsa [Member] | EU [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net             3    
Other current liabilities [Member] | Developed Technology Rights [Member] | Besponsa [Member] | United States [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net             $ 7    
[1] The changes in the gross carrying amount of Developed technology rights, Brands, Brands and other and IPR&D primarily reflect (i) the reclassification of $6.1 billion of Brands and Brands and other to Assets held for sale during the fourth quarter of 2018 (see Note 2C), (ii) the transfer of $2.7 billion from IPR&D to Developed technology rights to reflect the approval of Xtandi in the U.S. for the treatment of men with non-metastatic castration-resistant prostate cancer, which is being developed through a collaboration with Astellas (see Note 2A), (iii) $240 million of Developed technology rights recorded in connection with the EU approval of Mylotarg (see Note 7E), as well as impairments of $2.9 billion of Developed technology rights (see Note 4).