8-K

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM 8-K

CURRENT REPORT
Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported):  October 23, 2003

Isco, Inc.

(Exact name of registrant as specified in its charter)

Nebraska	0-4429	47-0461807
(State or other jurisdiction of incorporation)	(Commission File Number)	(IRS Employer Identification No.)

4700 Superior Street, Lincoln, NE  68504

(Address of Principal Executive Offices and Zip Code)

(402) 464-0231

(Registrant’s telephone number, including area code)

Not Applicable

(Former name or former address, if changed since last report)

Item 7.   Financial Statements and Exhibits

(c)Exhibits — The following exhibit is provided as part of the information furnished under Item 9 and Item 12 of this Current Report on Form 8-K:

Exhibit No.	Description
99.1	Press release — “Isco Reports Delay in Releasing Fiscal 2003 Results”

Item 9.   Regulation FD Disclosure

On October 23, 2003, Isco, Inc. issued a press release announcing the delay in releasing earnings and filing of its Form 10-K for the fiscal year ended July 25, 2003.  A copy of the news release is furnished herewith as Exhibit 99.1 and incorporated by reference herein.  This Current Report on Form 8-K and the press release attached hereto are being furnished by Isco, Inc. pursuant to Item 9 and Item 12 of Form 8-K.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	Isco, Inc.
Date:  October 23, 2003	BY: /s/ Vicki L. Benne
	Vicki L. Benne
	Chief Financial Officer and Treasurer

EX-99.1

Exhibit 99.1

FOR IMMEDIATE RELEASE: Thursday, October 23, 2003

CONTACT:	Vicki L. Benne
	Chief Financial Officer
	Isco, Inc.
	(402) 465-2097

ISCO REPORTS DELAY IN RELEASING FISCAL 2003 RESULTS

Lincoln, NE—Isco, Inc. (Nasdaq: ISKO) reported that it has delayed the release of its fiscal 2003 year-end results and has filed for a 15-day extension with the Securities and Exchange Commission for the filing of the 2003 fiscal year-end Form 10-K.  The delay is the result of waiting to obtain audited financials statements for Advanced Flow Technologies Partnership, Ltd. (AFTCO).  Isco, Inc. is a 50 percent partner in AFTCO and must include 50 percent of the earnings or loss of AFTCO in its earnings.  The completion of AFTCO’s financial statements and corresponding audit has been delayed due to the release of key management personnel within AFTCO, including its president.

“We are very disappointed that our fiscal year-end results and SEC filing must be delayed a short time due to events outside of our direct control,” said Doug Grant, president and chief operating officer.  “Isco is committed to reporting accurate results, and trusts that our shareholders will understand our decision to delay.”

Comments included in this News Release may include “forward-looking statements” within the meaning of the federal securities laws.  These statements as to anticipated future results are based on current expectations and are subject to a number of risks and uncertainties that could cause actual results to differ markedly from those projected or discussed here.  Such risks and uncertainties are detailed in Isco, Inc.’s Annual Report on Form 10-K filed with the SEC in October 2002 and are incorporated herein by reference.  Isco, Inc. cautions readers not to place undue reliance upon any such forward-looking statements, which speak only as of the date hereof.

News releases and other information regarding Isco, Inc. may be found at

www.isco.com on the Internet.

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