UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 15

CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER
SECTION 12(G) OF THE SECURITIES EXCHANGE ACT OF 1934 OR
SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(D)
OF THE SECURITIES EXCHANGE ACT OF 1934

Commission File Number [000-14429]

ISCO, INC.
(Exact name of registrant as specified in its charter)

4700 Superior Street
Lincoln, Nebraska 68504
(402) 464-0231
(Address, including zip code, and telephone number, including
area code, of registrant's principal executive offices)

Common Stock, Par Value $0.10
(Title of each class of securities covered by this Form)

NONE.
(Titles of all other classes of securities for which a duty to
file reports under Section 13(a) or 15(d) remains)

Please place an X in the box(es) to designate the appropriate rule provision(s) relied upon to terminate or suspend the duty to file reports:

Rule 12g-4(a)(1)(i)	ý	Rule 12h-3(b)(1)(i)	ý
Rule 12g-4(a)(1)(ii)	o	Rule 12h-3(b)(1)(ii)	o
Rule 12g-4(a)(2)(i)	o	Rule 12h-3(b)(2)(i)	o
Rule 12g-4(a)(2)(ii)	o	Rule 12h-3(b)(2)(ii)	o
		Rule 15d-6	o

Approximate number of holders of record as of the certification or notice date: 1

Pursuant to the requirements of the Securities Exchange Act of 1934, Isco, Inc. has caused this certification/notice to be signed on its behalf by the undersigned duly authorized person.

	ISCO, INC.
Date: June 18, 2004	By:	/s/  DOUGLAS M. GRANT
	Name:	Douglas M. Grant
	Title:	President and Chief Operating Officer