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Commitments and Contingencies - Additional Information (Detail)
 1 Months Ended 12 Months Ended
Jun. 23, 2016
USD ($)
Oct. 31, 2014
USD ($)
Aug. 15, 2013
USD ($)
ft²
Oct. 31, 2005
USD ($)
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Dec. 31, 2012
USD ($)
Dec. 31, 2011
USD ($)
Dec. 31, 2010
USD ($)
Loss Contingencies [Line Items]                    
Area under lease | ft²     4,419              
Term of lease period from lease commencement date     36 months              
Security deposit     $ 9,231              
Lease base rent payment     9,678              
Lease rent payment for second year     10,016              
Lease rent payment for third year     $ 10,367              
Total base rent over the lease term         $ 222,736          
Rent expense         125,203 $ 149,371        
Technology transaction fees       $ 4,000,000            
Milestone payment required as a sale of product       $ 10,000,000            
Future royalty percentage on net sales       5.00%            
Royalties to net sales of other product       4.00%            
Annual royalty fee under agreement       2.00%            
Minimum annual royalty fee current                   $ 100,000
Minimum annual royalty fee current in two years                 $ 100,000  
Minimum annual royalty fee current in three years               $ 150,000    
Minimum annual royalty fee current in four years             $ 150,000      
Minimum annual royalty fee current in five years           $ 200,000        
Minimum annual royalty fee current, thereafter         200,000          
Agreement amended canceled notice period       60 days            
BioRASI LLC [Member]                    
Loss Contingencies [Line Items]                    
Complaint filed seeking payments related to clinical trial   $ 500,000                
Provision related to clinical trial         $ 0          
March 1997 License Agreement [Member]                    
Loss Contingencies [Line Items]                    
Technology transaction fees       $ 50,000            
Milestone payment required as a sale of product       $ 1,800,000            
Future royalty percentage on net sales       3.00%            
Subsequent Event [Member] | Office Lease [Member]                    
Loss Contingencies [Line Items]                    
Lease agreement term 38 months                  
Monthly base rent in year one $ 3,500                  
Monthly base rent in year two 3,700                  
Monthly base rent in year three 3,800                  
Monthly base rent in the final two months of the agreement 3,900                  
Total base rent over the lease term $ 139,800