Income Taxes (Tables)

12 Months Ended

Dec. 31, 2015

Income Tax Disclosure [Abstract]

Summary of Net Deferred Tax Asset

Our net deferred tax asset consisted of the following at December 31, 2015 and 2014:

	December 31,
	2015			2014
Deferred tax asset:
Net operating loss carryforwards	$	42,315,384		$	41,512,011
Deferred compensation		1,474,625			1,082,211
Depreciation and amortization		1,010,636			1,161,055
Research and development credits		3,788,752			3,761,004
Accrued expenses		314,633			47,356
Impairment loss		850,334			730,830
Other		248,933			248,933
Total deferred tax assets		50,003,297			48,543,400
Less: Valuation allowance		(50,003,297	)		(48,543,400	)
Net deferred tax asset	$	—		$	—

Summary of Income Tax Provision (Benefit) from Income Taxes

The income tax provision (benefit) from income taxes consists of the following at December 31, 2015 and 2014:

	Years Ended December 31,
	2015			2014
Federal
Current	$	—		$	—
Deferred		(1,246,071	)		(6,333,053	)
State
Current
Deferred		(213,826	)		(2,739,746	)
Total		(1,459,897	)		(9,072,799	)
Change in valuation allowance		1,459,897			9,072,799
Income tax provision (benefit)	$	—		$	—

Summary of Provision for Income Taxes Using Statutory Federal Tax Rate

The provision for income taxes using the statutory federal tax rate as compared to our effective tax rate is summarized as follows:

	December 31,
	2015			2014
Federal income tax rate		(34.0	)%		(34.0	)%
State income tax rate, net of federal benefit		(4.8	)%		(14.6	)%
Deferred tax true-up		5.0		—
Other permanent differences		0.1	%	—		%
		(33.7	)%		(48.6	)%
Change in valuation allowance		33.7	%		48.6	%
		—	%		—	%