Income Taxes - Summary of Net Deferred Tax Asset (Detail) (USD $)	Dec. 31, 2014	Dec. 31, 2013
Deferred tax asset:
Net operating loss carryforwards	$ 41,512,011	$ 36,837,171
Deferred compensation	1,082,211	881,025
Depreciation and amortization	1,161,055	886,149
License impairment		437,187crxm_DeferredTaxAssetsLicenseImpairment
Research and development credits	3,761,004	194,132
Accrued expenses	47,356	97,326
Impairment of investments	730,830
Other	248,933us-gaap_DeferredTaxAssetsOther	137,611us-gaap_DeferredTaxAssetsOther
Total deferred tax assets	48,543,400us-gaap_DeferredTaxAssetsGross	39,470,601us-gaap_DeferredTaxAssetsGross
Less: Valuation allowance	(48,543,400)	(39,470,601)
Net deferred tax asset	$ 0us-gaap_DeferredTaxAssetsNet	$ 0us-gaap_DeferredTaxAssetsNet

Deferred tax assets depreciation and amortization.

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Deferred Tax Assets License Impairment

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Deferred Tax Assets Research And Development Tax Credits

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards.

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Amount after allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences not separately disclosed.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from reserves and accruals.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from compensation and benefits costs.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from estimated impairment losses.

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Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.

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