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Condensed Consolidated Statements Of Cash Flows (USD $)
3 Months Ended 99 Months Ended
Mar. 31, 2012
Mar. 31, 2011
Mar. 31, 2012
Since Inception [Member]
Cash Flows From Operating Activities      
Net loss $ (2,594,036) $ (1,688,640) $ (90,685,051)
Adjustments to reconcile net loss to net cash used in operating activities:      
Gain on sale of discontinued operation 0 0 (6,408,603)
Gain on sale of warrants 0 0 (518,622)
Loss on abandonment of leaseholds 0 0 135,344
Depreciation 23,880 26,635 2,027,185
Amortization-intangibles 0 0 2,696,193
Amortization-debt discount 0 0 5,291,019
Amortization-deferred financing costs 0 0 925,859
Amortization-technology and product license fee 33,602 22,727 135,875
Provision for obsolete inventory 0 0 200,000
Change in fair value of warrants (64,157) (88,170) (10,395,709)
Common stock and warrants issued for services and reimbursement of expenses 0 0 203,882
Stock based compensation expense 43,239 22,519 7,471,314
In-process purchased technology 0 0 2,027,529
Changes in operating assets and liabilities      
Accounts receivable (17,546) 0 61,442
Inventories (87,527) 0 (2,327,816)
Prepaid expenses and other assets (43,062) (10,732) (223,856)
Deposits 0 0 (189,750)
Accounts payable 439,881 (96,208) 2,326,189
Accrued liabilities 36,038 11,063 (182,186)
Deferred rent (12,960) (7,591) 105,353
Net cash used in operating activities (2,242,648) (1,808,397) (87,324,409)
Cash Flows From Investing Activities      
In-process technology purchased from Tissue Repair Company 0 0 (1,500,000)
Fee paid to list shares issued for technology and product license 0 0 (65,000)
Purchases of property and equipment 0 (1,358) (2,816,551)
Net cash used in investing activities 0 (1,358) (4,381,551)
Cash Flows From Financing Activities      
Proceeds from officer loan 0 0 62,882
Cash acquired in acquisitions 0 0 1,551,800
Restricted cash - collateral for letter of credit 150,000 100,000 (50,000)
Restricted cash - proceeds placed in escrow from sale of business 0 0 0
Proceeds from the exercise of warrants, net 0 0 1,258,448
Proceeds from debt financing agreement, net of debt issuance costs of $871,833 0 0 14,378,167
Proceeds from the sale of business unit 0 0 11,250,000
Repayment of debt 0 0 (15,750,000)
Proceeds from sales of common stock, net of issuance cost 6,441,891 0 88,075,185
Net cash provided by financing activities 6,591,891 100,000 100,776,482
Net increase (decrease) in cash 4,349,243 (1,709,755) 9,070,522
Cash and cash equivalents at beginning of period 4,721,279 6,644,054 0
Cash and cash equivalents at end of period 9,070,522 4,934,299 9,070,522
Supplemental Disclosures of Cash Flow Information:      
Cash paid for interest 1,395 1,431 1,390,196
Cash paid for income taxes 0 0 26,162
Non-Cash Activity:      
Subscription receivable for common shares 0 0 17,000
Common stock issued for repayment of loans 0 0 62,882
Stock issued for technology license fee 0 0 1,000,000
Net assets acquired for the issuance of common stock (exclusive of cash acquired) 0 0 5,824,000
Warrants exchanged for stock 0 0 (901,139)
Reclassification of derivative liabilities with expired price protection provisions (21,349) 0 (4,045,702)
Issuance of note for accrued milestone payment $ 0 $ 0 $ 500,000