EXHIBIT 32.2

CERTIFICATION PURSUANT TO

18 U.S.C. SECTION 1350,

AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the accompanying Quarterly Report of Greene County Bancshares, Inc. (the “Company”) on Form 10-Q for the quarter ended September 30, 2004 (the “Report”), I, William F. Richmond, Senior Vice President, Chief Financial Officer and Assistant Secretary of the Company, certify pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1)The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(1)The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

	/s/ William F. Richmond
		William F. Richmond
		Senior Vice President, Chief Financial
		Officer and Assistant Secretary
Date: November 5, 2004