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Note 13 - Warrants - Summary of Warrant Activity (Details) - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Warrants outstanding (in shares) 1,487,958 421,015
Warrants outstanding (in dollars per share) $ 9.39 $ 5,888
Warrants issued in connection with equity transactions (in shares) 9,231,628 1,147,595
Warrants issued in connection with equity transactions (in dollars per share) $ 3.46 $ 2.03
Warrants exercised (in shares) (7,617,147) (17,857)
Warrants exercised (in dollars per share) $ 2.89 $ 0.14
Warrants expired (in shares) (44,037) (62,795)
Warrants expired (in dollars per share) $ 174.58 $ 209.23
Warrants outstanding (in shares) 3,058,402 1,487,958
Warrants outstanding (in dollars per share) $ 5.29 $ 9.39
Aggregate intrinsic value of outstanding warrants $ 37,143  
Weighted average remaining contractual terms (Year) 3 years 182 days