Note 12 - Earn-out Milestone Liability (Tables)

12 Months Ended

Dec. 31, 2016

Notes Tables

Schedule of Changes in Earn out Milestone Liabilities [Table Text Block]

Balance at January 1, 2015	$	13,663,710
Non-cash loss from the adjustment for the change in fair value included in 2015 net loss		257,702
Balance at December 31, 2015	$	13,921,412
Non-cash gain from the adjustment for the change in fair value included in 2016 net loss		(733,186	)
Balance at December 31, 2016	$	13,188,226