Income Taxes - Narrative (Details) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2019	Oct. 01, 2019
Operating Loss Carryforwards [Line Items]
Increase in valuation allowance	$ 3,272,600,000	$ 4,678,000,000
Net operating loss carryforwards, permanent loss of tax benefit			$ 30,880,000
R&D credit	2,154,000	2,154,000
Unrecognized tax benefits, income tax penalties and interest accrued	0	0
Unrecognized tax benefits, income tax penalties and interest expense	0	0
Federal
Operating Loss Carryforwards [Line Items]
Net operating loss carryforwards	135,517,000	128,447,000
NOL subject to expiration	75,456,000
State
Operating Loss Carryforwards [Line Items]
Net operating loss carryforwards	$ 104,886,000	$ 101,035,000
Collaboration Products
Operating Loss Carryforwards [Line Items]
Noncontrolling interest, ownership percentage by parent				75.00%