Income Taxes - Narrative (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Oct. 01, 2019
Operating Loss Carryforwards [Line Items]
Increase (decrease) in valuation allowance	$ 4,678,000	$ (4,005,000)
Net operating loss carryforwards, permanent loss of tax benefit			$ 30,880,000
Unrecognized tax benefits, income tax penalties and interest accrued	0	0
Unrecognized tax benefits, income tax penalties and interest expense	0	0
United Kingdom
Operating Loss Carryforwards [Line Items]
Deduction amount	7,260,000
Federal
Operating Loss Carryforwards [Line Items]
Net operating loss carryforwards	128,104,000	110,401,000
NOL subject to expiration	76,165,000	76,500,000
State
Operating Loss Carryforwards [Line Items]
Net operating loss carryforwards	$ 114,696,000	$ 94,223,000
Collaboration Products
Operating Loss Carryforwards [Line Items]
Noncontrolling interest, ownership percentage by parent				75.00%