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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 C4lJ7swQaB0RZAuBZX1vjdf390ES8yOXhQxH9HYkmFIHojDBWRf148kWtIJ6jjnm
 5lUhm2GeloSPhFC0F05LBA==

<SEC-DOCUMENT>9999999995-09-003512.txt : 20091217
<SEC-HEADER>9999999995-09-003512.hdr.sgml : 20091217
<ACCEPTANCE-DATETIME>20091217001518
ACCESSION NUMBER:		9999999995-09-003512
CONFORMED SUBMISSION TYPE:	EFFECT
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20091216
DATE AS OF CHANGE:		20091217
EFFECTIVENESS DATE:		20091216

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MIDSOUTH BANCORP INC
		CENTRAL INDEX KEY:			0000745981
		STANDARD INDUSTRIAL CLASSIFICATION:	NATIONAL COMMERCIAL BANKS [6021]
		IRS NUMBER:				721020809
		STATE OF INCORPORATION:			LA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		EFFECT
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-163361
		FILM NUMBER:		091245966

	BUSINESS ADDRESS:	
		STREET 1:		102 VERSAILLES BLVD
		STREET 2:		VERSAILLES CENTRE
		CITY:			LAFAYETTE
		STATE:			LA
		ZIP:			70501
		BUSINESS PHONE:		3182378343

	MAIL ADDRESS:	
		STREET 1:		102 VERSAILLES BLVD
		CITY:			LAFAYETTE
		STATE:			LA
		ZIP:			70501
</SEC-HEADER>
<DOCUMENT>
<TYPE>EFFECT
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0101</schemaVersion>

    <submissionType>EFFECT</submissionType>

    <act>33</act>

    <testOrLive>LIVE</testOrLive>

    <effectiveData>
        <finalEffectivenessDispDate>2009-12-16</finalEffectivenessDispDate>
        <finalEffectivenessDispTime>14:00:00</finalEffectivenessDispTime>
        <form>S-1</form>
        <filer>
            <cik>0000745981</cik>
            <entityName>MIDSOUTH BANCORP INC</entityName>
            <fileNumber>333-163361</fileNumber>
        </filer>
    </effectiveData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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