Exhibit 32.1

                      CERTIFICATION PURSUANT TO
           SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of MidSouth
Bancorp, Inc. (the "Company") on Form 10-Q for the
period ending March 31, 2004(the "Report"), I, C.R.
Cloutier, Chief Executive Officer of the Company, certify
that:

     (1) The Report fully complies with the requirements
of section 13(a) or 15(d) of the Securities Exchange Act of
1934; and

     (2) The information contained in the Report fairly
presents, in all material respects, the financial condition and
result of operations of the Company.


/s/ C. R. Cloutier
________________________
C.R. Cloutier
Chief Executive Officer
May 14, 2004