-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 CehfgfLw/G424+nuZzN5wSz6/itrbUHE3ZCinkvIExWHDOpCBN6oIVad0/n01qzs
 E6guNOekE8YVnODMf2lxDQ==

<SEC-DOCUMENT>0000745981-04-000031.txt : 20041015
<SEC-HEADER>0000745981-04-000031.hdr.sgml : 20041015
<ACCEPTANCE-DATETIME>20041015181911
ACCESSION NUMBER:		0000745981-04-000031
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20041014
FILED AS OF DATE:		20041015
DATE AS OF CHANGE:		20041015

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Weir Lonnie C
		CENTRAL INDEX KEY:			0001305110

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-11826
		FILM NUMBER:		041081947

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		337-267-4202

	MAIL ADDRESS:	
		STREET 1:		P. O. BOX 3745
		CITY:			LAFAYETTE
		STATE:			LA
		ZIP:			70502

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MIDSOUTH BANCORP INC
		CENTRAL INDEX KEY:			0000745981
		STANDARD INDUSTRIAL CLASSIFICATION:	NATIONAL COMMERCIAL BANKS [6021]
		IRS NUMBER:				721020809
		STATE OF INCORPORATION:			LA
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		102 VERSAILLES BLVD
		STREET 2:		VERSAILLES CENTRE
		CITY:			LAFAYETTE
		STATE:			LA
		ZIP:			70501
		BUSINESS PHONE:		3182378343

	MAIL ADDRESS:	
		STREET 1:		102 VERSAILLES BLVD
		CITY:			LAFAYETTE
		STATE:			LA
		ZIP:			70501
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>primary_doc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2004-10-14</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000745981</issuerCik>
        <issuerName>MIDSOUTH BANCORP INC</issuerName>
        <issuerTradingSymbol>MSL</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001305110</rptOwnerCik>
            <rptOwnerName>Weir Lonnie C</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>102 VERSAILLES BLVD.</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>LAFAYETTE</rptOwnerCity>
            <rptOwnerState>LA</rptOwnerState>
            <rptOwnerZipCode>70501</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>6233</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>Lonnie C. Weir</signatureName>
        <signatureDate>2004-10-15</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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