<SEC-DOCUMENT>0001104659-22-084740-index.html : 20220801
<SEC-HEADER>0001104659-22-084740.hdr.sgml : 20220801
<ACCEPTANCE-DATETIME>20220801164856
ACCESSION NUMBER:		0001104659-22-084740
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		12
FILED AS OF DATE:		20220801
DATE AS OF CHANGE:		20220801

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			APPLIED DNA SCIENCES INC
		CENTRAL INDEX KEY:			0000744452
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MISCELLANEOUS BUSINESS SERVICES [7380]
		IRS NUMBER:				592262718
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-266223
		FILM NUMBER:		221125477

	BUSINESS ADDRESS:	
		STREET 1:		50 HEALTH SCIENCES DRIVE
		CITY:			STONY BROOK
		STATE:			NY
		ZIP:			11790
		BUSINESS PHONE:		631-240-8800

	MAIL ADDRESS:	
		STREET 1:		50 HEALTH SCIENCES DRIVE
		CITY:			STONY BROOK
		STATE:			NY
		ZIP:			11790

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PROHEALTH MEDICAL TECHNOLOGIES INC
		DATE OF NAME CHANGE:	20010504

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DCC ACQUISITION CORP
		DATE OF NAME CHANGE:	19990211

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DATALINK CAPITAL CORP/TX/
		DATE OF NAME CHANGE:	19980306
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1/A
<SEQUENCE>1
<FILENAME>tm2222270d1_s1a.htm
<DESCRIPTION>S-1/A
<TEXT>
Document 1 - file: tm2222270d1_s1a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.9
<SEQUENCE>2
<FILENAME>tm2222270d1_ex4-9.htm
<DESCRIPTION>EXHIBIT 4.9
<TEXT>
Document 2 - file: tm2222270d1_ex4-9.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.10
<SEQUENCE>3
<FILENAME>tm2222270d1_ex4-10.htm
<DESCRIPTION>EXHIBIT 4.10
<TEXT>
Document 3 - file: tm2222270d1_ex4-10.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.11
<SEQUENCE>4
<FILENAME>tm2222270d1_ex4-11.htm
<DESCRIPTION>EXHIBIT 4.11
<TEXT>
Document 4 - file: tm2222270d1_ex4-11.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>5
<FILENAME>tm2222270d1_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 5 - file: tm2222270d1_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.42
<SEQUENCE>6
<FILENAME>tm2222270d1_ex10-42.htm
<DESCRIPTION>EXHIBIT 10.42
<TEXT>
Document 6 - file: tm2222270d1_ex10-42.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>7
<FILENAME>tm2222270d1_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 7 - file: tm2222270d1_ex23-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>8
<FILENAME>tm2222270d1_ex107.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 8 - file: tm2222270d1_ex107.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>tm2222270d1_s1a1img01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: tm2222270d1_s1a1img01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>tm2222270d1_s1a2img01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: tm2222270d1_s1a2img01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>tm2222270d1_ex5-1img01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: tm2222270d1_ex5-1img01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>tm2222270d1_ex5-1img02.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: tm2222270d1_ex5-1img02.jpg

</DOCUMENT>
</SEC-DOCUMENT>