Stockholders' Equity (Details) - USD ($) $ in Thousands	1 Months Ended		3 Months Ended
	Mar. 31, 2024	Nov. 30, 2023	Mar. 31, 2024	Mar. 31, 2023
Increase (Decrease) in Stockholders' Equity
Balance, beginning			$ 429,171	$ 326,204
Balance, beginning (in shares)			55,883,377
Shares issued under stock option and employee stock purchase plans			$ 3,814	694
Shares issued in underwritten offering, net			432,298
Stock-based compensation			7,202	4,340
Unrealized (loss) gain on marketable securities			(1,064)	863
Net loss			(32,808)	(29,361)
Balance, ending	$ 838,613		$ 838,613	302,740
Balance, ending (in shares)	65,910,548		65,910,548
Net proceeds from sale of common stock			$ 432,298
Underwritten Public Offering
Increase (Decrease) in Stockholders' Equity
Common stock issued (in shares)	9,798,000	8,538,750
Net proceeds from sale of common stock	$ 432,300	$ 216,200
Common Stock
Increase (Decrease) in Stockholders' Equity
Balance, beginning			$ 56	$ 47
Balance, beginning (in shares)			55,883,377	47,200,695
Shares issued under stock option and employee stock purchase plans (in shares)			229,171	43,986
Shares issued in underwritten offering, net			$ 10
Shares issued in underwritten offering, net (in shares)			9,798,000
Balance, ending	$ 66		$ 66	$ 47
Balance, ending (in shares)	65,910,548		65,910,548	47,244,681
Additional Paid-In Capital
Increase (Decrease) in Stockholders' Equity
Balance, beginning			$ 1,823,168	$ 1,580,829
Shares issued under stock option and employee stock purchase plans			3,814	694
Shares issued in underwritten offering, net			432,288
Stock-based compensation			7,202	4,340
Balance, ending	$ 2,266,472		2,266,472	1,585,863
Accumulated Other Comprehensive Income
Increase (Decrease) in Stockholders' Equity
Balance, beginning			3,308	1,260
Unrealized (loss) gain on marketable securities			(1,064)	863
Balance, ending	2,244		2,244	2,123
Accumulated Deficit
Increase (Decrease) in Stockholders' Equity
Balance, beginning			(1,397,361)	(1,255,932)
Net loss			(32,808)	(29,361)
Balance, ending	$ (1,430,169)		$ (1,430,169)	$ (1,285,293)