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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Stock options      
Net loss per share      
Potentially dilutive common shares not been included in net loss per common share calculations because the effect would have been anti-dilutive 5,085,662 4,077,667 3,042,229